Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors.

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Summary

Imatinib induced a sustained objective response in more than half of patients with an advanced unresectable or metastatic gastrointestinal stromal tumor, indicating that inhibition of the KIT signal-transduction pathway is a promising treatment for advanced gastrointestinalStromal tumors, which resist conventional chemotherapy.

Type
article
Published
2002-08-15
Cited by
4,312
References
24
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Open access

Keywords

Medicine, Imatinib, Imatinib mesylate, Tyrosine-kinase inhibitor, Tolerability

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