Prevalence of amplification of the oncogenes c-myc, HER2/neu, and int-2 in one thousand human breast tumours: correlation with steroid receptors.

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Summary

Amplification of c-myc, HER2/neu and int-2/bcl-1 genes in a series of 1052 collected human breast tumours showed a large fluctuation, which could be attributed to the study of relatively small series of tumours, to selection of subgroups of patients, or, especially in retrospective studies, to Selection of tumour material from the tumour-bank.

Type
article
Published
1992-02-01
Cited by
139
References
28

Keywords

Gene duplication, Oncogene, INT, Breast cancer, Internal medicine

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