Ion Channel Regulation by Lipid Bilayers: Theory & Simulation of Deformed Membranes around Gramicidin A

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Summary

GA channels were used as a surrogate for conformational transitions of large membrane proteins that perturb the host bilayer, and it is shown that gA monomer insertion produces similar contributions to dF/dR−1 independent of bilayer type, and gA dimerization increases dF/(dR)−1 systematically with bilayer thickness.

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article
Published
2015-01-27
Cited by
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Keywords

Lipid bilayer mechanics, Bilayer, Lipid bilayer, Lipid bilayer phase behavior, Gramicidin

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