SOX9 expression is a general marker of basal cell carcinoma and adnexal‐related neoplasms
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Summary
This work tested whether activation of SOX9 is a general feature of BCC, or whether it could be used as a biomarker to better define subtypes of these skin tumors, and investigatedSOX9 expression in other skin epidermal tumors.
- Type
- article
- Published
- 2008-04-01
- Cited by
- 99
- References
- 33
- Access
- Open access
- OpenAlex
- https://openalex.org/W2014218119
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11783647
Keywords
Basal cell carcinoma, Pathology, SOX9, Biology, H&E stain
References
- Eccrine Porocarcinoma (Malignant Eccrine Poroma): A Clinicopathologic Study of 69 Cases
- Expression of SOX9 and SOX10 in Central Neuroepithelial Tumor
- Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours
- Genetics and risk factors for basal cell carcinoma
- Sox genes and cancer
- Hedgehog signalling in skin development and cancer
- Sonic hedgehog signaling is essential for hair development.
- Indian hedgehog and β-catenin signaling: Role in the sebaceous lineage of normal and neoplastic mammalian epidermis
- Skin adnexal neoplasms—part 1: An approach to tumours of the pilosebaceous unit
- Hedgehog signaling regulates sebaceous gland development.
- Immunohistochemical Analysis of Sox9 in Ovarian Sertoli Cell Tumors and Other Tumors in the Differential Diagnosis
- Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice
- Basal cell carcinomas in mice overexpressing Gli2 in skin
- Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog.
- Essential role for Sonic hedgehog during hair follicle morphogenesis.
- Basal cell carcinoma: a dermatopathological and molecular biological update
- Skin adnexal neoplasms—part 2: An approach to tumours of cutaneous sweat glands
- Basal Cell Carcinoma
- Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1.
- Dermoscopy patterns of fibroepithelioma of pinkus.
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- The Skin: A Home to Multiple Classes of Epithelial Progenitor Cells
- SOX9, a potential tumor suppressor in cervical cancer, transactivates p21WAF1/CIP1 and suppresses cervical tumor growth
- Upregulation of SNAI2 and SOX9 mRNA versus downregulation of eight other EMT/stemness related genes in basal cell carcinoma
- THE ROLE OF SOX9 DURING HUMAN PANCREAS DEVELOPMENT
- The role of GLI2 in human basal cell carcinoma tumourigenesis
- Mapping the expression of epithelial hair follicle stem cell‐related transcription factors LHX2 and SOX9 in the human hair follicle
- Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tumor Initiation and Invasion.
- Sox9 Expression in Canine Epithelial Skin Tumors
- Basal cell carcinoma and pilomatrixoma mirror human follicular embryogenesis as reflected by their differential expression patterns of SOX9 and β‐catenin
- Basal cell carcinoma: cell of origin, cancer stem cell hypothesis and stem cell markers
- C/EBPα and β couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation
- Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation
- Expression and Functional Role of Sox9 in Human Epidermal Keratinocytes
- Sox9, more than a marker of the outer root sheath: spatiotemporal expression pattern during human cutaneous embryogenesis
- Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.
- Evaluation of SOX9 Expression in Pancreatic Ductal Adenocarcinoma and Intraductal Papillary Mucinous Neoplasm
- Cancer Genomics Identifies Regulatory Gene Networks Associated with the Transition from Dysplasia to Advanced Lung Adenocarcinomas Induced by c-Raf-1
- Basal cell carcinoma arising within a seborrheic keratosis with respect to immunohistochemical characteristics.
- cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment.
- Epidermal stem cells: an update on their potential in regenerative medicine