Nonchromosomal antibiotic resistance in bacteria: genetic transformation of Escherichia coli by R-factor DNA.

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Summary

Covalently-closed, catenated, and open (nicked) circular forms of R-factor DNA are all effective in transformation, but denaturation and sonication abolish the transforming ability of R.factor DNA in this system.

Type
article
Published
1972-08-01
Cited by
2,606
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Keywords

Transformation (genetics), DNA, Escherichia coli, Bacteria, Biology

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