Evaluating statistical analyses and reproducibility of microbial mutagenicity assays.
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Summary
The NCI/NTP has completed the first phase of a 4-laboratory study on the reproducibility of testing chemicals for mutagenicity in the Salmonella/microsome assay, and a report of the statistical analysis of some of that data is reported.
- Type
- article
- Published
- 1981-06-01
- Cited by
- 136
- References
- 6
- OpenAlex
- https://openalex.org/W2013807142
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28320868
Keywords
Reproducibility, Spurious relationship, Homogeneity (statistics), Statistics, Percentile
References
- Design and analysis of experiments on mutagenicity. II. Assays involving microorganisms.
- A statistical treatment of the ames mutagenicity assay
- Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.
- Recommendations on data production and analysis using the Salmonella/microsome mutagenicity assay
- Simultaneous Statistical Inference
- Simultaneous Statistical Inference
Cited by
- An interlaboratory study of an EPA/Ames/Salmonella test protocol.
- A comparison of alternative measures of mutagenic potency in the Salmonella (Ames) test.
- Biodegradation of simple chemical mixtures in soil
- UKEMS collaborative genotoxicity trial. Bacterial mutation tests of 4-chloromethylbiphenyl, 4-hydroxymethylbiphenyl and benzyl chloride: analysis of data from 17 laboratories.
- Bioactive-guided Identification of Labdane Diterpenoids from Aerial Parts of Aristeguietia glutinosa as anti-Trypanosoma cruzi agents
- Classification of compounds by cluster analysis of Ames test data.
- Studies of mutagenic activity of fluorescent DNAsensitive monomethinecyanine and carbocyanine dyes in Ames test
- Development of bis-thiazoles as inhibitors of triosephosphate isomerase from Trypanosoma cruzi. Identification of new non-mutagenic agents that are active in vivo.
- The Salmonella typhimurium/mammalian microsomal assay. A report of the U.S. Environmental Protection Agency Gene-Tox Program.
- Chemical and biological characterization of hazardous industrial waste. I. Prokaryotic bioassays and chemical analysis of a wood-preserving bottom-sediment waste.
- Characterization of particulate emissions from in-use gasoline-fueled motor vehicles
- Statistical methods for short-term tests in genetic toxicology: the first fifteen years.
- Genotoxicity Assessment of Wood-Preserving Waste–Contaminated Soil Undergoing Bioremediation
- Bladder freeze ulceration and sodium saccharin feeding in the rat: examination for urinary nitrosamines, mutagens and bacteria, and effects on hepatic microsomal enzymes.
- Discovery of new orally effective analgesic and anti-inflammatory hybrid furoxanyl N-acylhydrazone derivatives.
- Modulation of mitomycin C mutagenicity on Saccharomyces cerevisiae by glutathione, cytochrome P-450, and mitochondria interactions.
- Antimutagenicity of polyphenol-rich fractions from Sorghum bicolor grain
- Mutagens in urine sampled repetitively from municipal refuse incinerator workers and water treatment workers.
- Urinary mutagens in cosmetologists and dental personnel.
- Chemical and toxicological studies of products resulting from sorbic acid and methylamine interaction in food conditions
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