Ancestral reconstruction of segmental duplications reveals punctuated cores of human genome evolution

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Summary

It is hypothesized that the rapid expansion and fixation of some intrachromosomal segmental duplications during great-ape evolution has been due to the selective advantage conferred by these genes and transcripts embedded within these core duplications.

Type
article
Published
2007-11-01
Cited by
227
References
41

Keywords

Biology, Gene duplication, Segmental duplication, Non-allelic homologous recombination, Genome

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