Neuronal sensitization for histamine-induced itch in lesional skin of patients with atopic dermatitis.
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Summary
The results suggest a decreased activation of peripheral pruriceptors in patients with atopic dermatitis, and the massively increased itch in lesional skin of patients with AD might be based on sensitization for itch in the spinal cord rather than in primary afferent neurons.
- Type
- article
- Published
- 2003-11-01
- Cited by
- 115
- References
- 34
- OpenAlex
- https://openalex.org/W2012514045
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36081954
Keywords
Medicine, Sensitization, Axon reflex, Histamine, Atopic dermatitis
References
- Itch and Atopic Dermatitis: An Overview
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- Patients' perception of itch induced by histamine, compound 48/80 and wool fibres in atopic dermatitis.
- Itch and atopic dermatitis: clinical and experimental studies.
- Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch
- Neural Mechanisms of Cutaneous Nociceptive Pain
- Effect of topical capsaicin on the cutaneous reactions and itching to histamine in atopic eczema compared to healthy skin
- Histamine-induced itch converts into pain in neuropathic hyperalgesia
- The nature and the distribution of afferent fibres provided with the axon reflex arrangement.
- Response to systemic HIV viral load suppression correlates with psychomotor speed performance
- Laser Doppler measurements of skin vasodilation elicited by percutaneous electrical stimulation of nociceptors in humans.
- Opiate and H1 antagonist effects on histamine induced pruritus and alloknesis
- Histamine and cutaneous nociception: histamine-induced responses in patients with atopic eczema, psoriasis and urticaria.
- Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin.
- Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin.
- Skin reactions and itch sensation induced by epicutaneous histamine application in atopic dermatitis and controls.
- EPILEPTIFORM ATTACKS DUE TO MYXOMA OF THE RIGHT AURICLE
- Specific C-Receptors for Itch in Human Skin
- Skin reactivity to neuropeptides in atopic dermatitis
- Attenuation of experimental pruritus and mechanically evoked dysesthesiae in an area of cutaneous allodynia.
Cited by
- Increased levels of palmitoylethanolamide and other bioactive lipid mediators and enhanced local mast cell proliferation in canine atopic dermatitis
- アトピー性皮膚炎患者におけるヒスタミン誘発反応に対する抗ヒスタミン薬の有効性に関する検討 ―塩酸フェキソフェナジン，塩酸オロパタジンおよび塩酸セチリジンの比較検討―
- Neurophysiologie des Pruritus
- STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch
- Chapter 18 Itch and cold allodynia.
- Temperature modulated histamine‐itch in lesional and nonlesional skin in atopic eczema – a combined psychophysical and neuroimaging study
- Psychophysical measurements of itch and nociceptive sensations in an experimental model of allergic contact dermatitis
- Pathophysiology and therapy of pruritus in allergic and atopic diseases
- Vergleichende psychologische Aspekte von Juckreiz und Schmerz
- Increased frequencies of IL‐31‐producing T cells are found in chronic atopic dermatitis skin
- Role of Spinal Neurotransmitter Receptors in Itch: New Insights into Therapies and Drug Development
- Basic Mechanisms of Itch
- Interleukin-31 (L-31) causes alloknesis: pain-stimulation becomes itch-stimulation in mouse skin
- Medicinal Herb Extracts Attenuate 1-Chloro-2,4dinitrobenzene-induced Development of Atopic Dermatitis-like Skin Lesions
- Enhanced scratching evoked by PAR-2 agonist and 5-HT but not histamine in a mouse model of chronic dry skin itch
- Pruritus measurement and treatment
- Updated neurophysiology of itch.
- Mechanisms and potential therapeutic targets in allergic inflammation: recent insights
- Itch and nerve fibers with special reference to atopic dermatitis: Therapeutic implications
- Analysis of the mechanism for the development of allergic skin inflammation and the application for its treatment: mechanisms and management of itch in atopic dermatitis.
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