Safety and Efficacy of Flumazenil for Reversal of Iatrogenic Benzodiazepine-Associated Delirium Toxicity During Treatment of Alcohol Withdrawal, a Retrospective Review at One Center
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Summary
Flumazenil diagnosed benzodiazepine delirium during the treatment of AWS and improved impairments in cognition and behavior without serious or life-threatening adverse events in patients.
- Type
- review
- Published
- 2014-03-12
- Cited by
- 25
- References
- 37
- Access
- Open access
- OpenAlex
- https://openalex.org/W2012318170
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9599930
Keywords
Medicine, Flumazenil, Benzodiazepine, Delirium, Delirium tremens
References
- Comparative pharmacokinetics of submucosal vs. intravenous flumazenil (Romazicon) in an animal model.
- Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy.
- Flumazenil, naloxone and the 'coma cocktail'.
- Benzodiazepine receptor antagonists for hepatic encephalopathy.
- Stability and pharmacokinetics of flumazenil in the rat
- Use of flumazenil in the treatment of drug overdose: a double-blind and open clinical study in 110 patients.
- Midazolam and flumazenil pharmacokinetics and pharmacodynamics following simultaneous administration to human volunteers
- Etiologic and Outcome Profiles in Hypoactive and Hyperactive Subtypes of Delirium
- The Toxicologist and Delirium: Flumazenil as a Diagnostic and Therapeutic Tool for Delirium During the Course of Alcohol Withdrawal
- An approach to the patient with substance use and abuse.
- Reassessing the methods of medical record review studies in emergency medicine research.
- Monitoring Sedation, Agitation, Analgesia, Neuromuscular Blockade, and Delirium in Adult ICU Patients
- Pharmacokinetics of flumazenil and midazolam.
- Morbidity Profiles Following Thoracoscopic Segmentectomy and Lobectomy for Clinical Stage I Non-small Cell Lung Cancer
- The use of flumazenil after midazolam-induced conscious sedation
- Factor analysis supports the evidence of existing hyperactive and hypoactive subtypes of delirium
- Comparison and agreement between the Richmond Agitation-Sedation Scale and the Riker Sedation-Agitation Scale in evaluating patients' eligibility for delirium assessment in the ICU.
- A poison center's ten-year experience with flumazenil administration to acutely poisoned adults.
- Prospective evaluation of the Sedation-Agitation Scale for adult critically ill patients.
- Pharmacokinetics and Clinical Use of Flumazenil (Ro 15-1788)
Cited by
- Flumazenil, naloxone and the 'coma cocktail'.
- The Toxicologist and Delirium: Flumazenil as a Diagnostic and Therapeutic Tool for Delirium During the Course of Alcohol Withdrawal
- Ethanol Toxicity During Brain Development: Alterations of Excitatory Synaptic Transmission in Immature Organotypic Hippocampal Slice Cultures.
- Alcohol withdrawal syndrome in medical patients
- Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil
- Acute neurotoxicology of drugs of abuse.
- Toxicologic Emergencies in Patients with Mental Illness: When Medications Are No Longer Your Friends.
- Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study
- Antagonizing the errors of history: bedside experience with flumazenil
- The ASAM Clinical Practice Guideline on Alcohol Withdrawal Management.
- In response to: Safety and Efficacy of Flumazenil for Reversal of Iatrogenic Benzodiazepine-Associated Delirium Toxicity During Treatment of Alcohol Withdrawal, a Retrospective Review at One Center
- Severe diaphoresis and fever during alcohol withdrawal cause hypovolemic shock: case report
- Return Encounters in Emergency Department Patients Treated with Phenobarbital Versus Benzodiazepines for Alcohol Withdrawal
- Chlordiazepoxide-induced delirium in a patient undergoing alcohol withdrawal: a case report
- Emergency Department Management of Patients With Alcohol Intoxication, Alcohol Withdrawal, and Alcohol Use Disorder: A White Paper Prepared for the American Academy of Emergency Medicine.
- GABAergic Psychoactive Substance-Induced Delirium: Narrative Literature Review
- Incidence of Adverse Events Using Flumazenil in Patients With Iatrogenic Benzodiazepine Delirium: A Retrospective Study
- Low risk of adverse events associated with flumazenil administration: a retrospective poison center analysis of acutely poisoned patients
- The Effect of Methylphenidate on The Consciousness Level of Intoxicated Patients; a Double-Blind Clinical Trial
- Dexmedetomidine infusions and phenobarbital in the treatment of an unusual presentation of benzodiazepine-resistant alcohol withdrawal
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