A New Mouse Model for the Study of Human Breast Cancer Metastasis
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Summary
A novel in vivo model using human breast cancer xenografts in NOD scid gamma (NSG) mice enables the study of the entire metastatic process from the proper anatomical site, providing an important new approach to examine the mechanisms underlying breast cancer metastasis.
- Type
- article
- Published
- 2012-10-31
- Cited by
- 162
- References
- 21
- Access
- Open access
- OpenAlex
- https://openalex.org/W2012296077
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2342980
Keywords
Breast cancer, Metastasis, Cancer, Cancer research, CA15-3
References
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- The emergence of lncRNAs in cancer biology
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- Vascular Endothelial Growth Factor Mediates Intracrine Survival in Human Breast Carcinoma Cells through Internally Expressed VEGFR1/FLT1
- Human Lymphoid and Myeloid Cell Development in NOD/LtSz-scid IL2Rγnull Mice Engrafted with Mobilized Human Hemopoietic Stem Cells 12
- Cancer Statistics, 2010
- Isolation of two human tumor epithelial cell lines from solid breast carcinomas.
- Reversal of the Estrogen Receptor–Negative Phenotype in Breast Cancer and Restoration of Antiestrogen Response
Cited by
- A novel microfluidic model can mimic organ-specific metastasis of circulating tumor cells
- A versatile 3D tissue matrix scaffold system for tumor modeling and drug screening
- S6K1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer.
- Function of Long Noncoding RNAs in Breast Cancer
- Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis
- Correlation between Plasma DNA and Tumor Status in an Animal Model
- Detection of breast surgical margins with optical coherence tomography imaging: a concept evaluation study
- Differential Post-Surgical Metastasis and Survival in SCID, NOD-SCID and NOD-SCID-IL-2Rγnull Mice with Parental and Subline Variants of Human Breast Cancer: Implications for Host Defense Mechanisms Regulating Metastasis
- Mitochondrial ATAD3A combines with GRP78 to regulate the WASF3 metastasis-promoting protein
- Tumour-initiating capacity is independent of epithelial–mesenchymal transition status in breast cancer cell lines
- A Murine Model for Metastatic Conjunctival Melanoma.
- Gasdermin-B Promotes Invasion and Metastasis in Breast Cancer Cells
- Orthotopic injection of breast cancer cells into the mammary fat pad of mice to study tumor growth.
- Infiltrating S100A8+ myeloid cells promote metastatic spread of human breast cancer and predict poor clinical outcome
- Expression of Multidrug Resistance Transporter ABCB5 in a Murine Model of Human Conjunctival Melanoma
- RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment
- Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium
- Luminal breast cancer metastases and tumor arousal from dormancy are promoted by direct actions of estradiol and progesterone on the malignant cells
- Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures
- Low coherence interferometry approach for aiding fine needle aspiration biopsies
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