Δ9-Tetrahydrocannabinol Prevents Methamphetamine-Induced Neurotoxicity
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Summary
Results indicate that Δ9-THC reduces METH-induced brain damage via inhibition of nNOS expression and astrocyte activation through CB1-dependent and independent mechanisms, respectively.
- Type
- article
- Published
- 2014-05-20
- Cited by
- 28
- References
- 74
- Access
- Open access
- OpenAlex
- https://openalex.org/W2012235026
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18182667
Keywords
Meth-, Methamphetamine, Neurotoxicity, Pharmacology, Neuroprotection
References
- Cannabinoids and Parkinson's disease.
- Decreased frontal N-acetylaspartate levels in adolescents concurrently using both methamphetamine and marijuana
- Formation of N-acyl-phosphatidylethanolamines and N-acetylethanolamines: proposed role in neurotoxicity.
- The rat brain in stereotaxic coordinates: Authors: George Paxinos & Charles Watson Academic Press Australia, 1982 Softback, 154 pages (including 71 plates), 35.00 Aust $
- The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses.
- Massive accumulation of N‐acylethanolamines after stroke. Cell signalling in acute cerebral ischemia?
- Post‐ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death
- Peroxynitrite plays a role in methamphetamine‐induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper–zinc superoxide dismutase
- Blockade of cannabinoid CB1 receptor function protects against in vivo disseminating brain damage following NMDA‐induced excitotoxicity
- Cannabinoids inhibit the release of [3H]glutamate from rodent hippocampal synaptosomes via a novel CB1 receptor‐independent action
- Vanilloid VR1 receptor is involved in rimonabant‐induced neuroprotection
- Endocannabinoids and Traumatic Brain Injury
- Methamphetamine influences on brain and behavior: Unsafe at any speed?
- Changes in hippocampal morphology following chronic treatment with the synthetic cannabinoid WIN 55,212-2.
- Methamphetamine Induces Long-Term Alterations in Reactivity to Environmental Stimuli: Correlation with Dopaminergic and Serotonergic Toxicity
- Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment.
- Cognitive Performance of Current Methamphetamine and Cocaine Abusers
- Distinct regulation of nNOS and iNOS by CB2 receptor in remote delayed neurodegeneration
- Methamphetamine neurotoxicity increases brain expression and alters behavioral functions of CB₁ cannabinoid receptors.
- Sativex-like combination of phytocannabinoids is neuroprotective in malonate-lesioned rats, an inflammatory model of Huntington's disease: role of CB1 and CB2 receptors.
Cited by
- Influence of caffeine on 3,4‐methylenedioxymethamphetamine‐induced dopaminergic neuron degeneration and neuroinflammation is age‐dependent
- Total bile acids in the maternal and fetal compartment in relation to placental ABCG2 expression in preeclamptic pregnancies complicated by HELLP syndrome.
- HIV-1, methamphetamine and astrocytes at neuroinflammatory Crossroads
- Influence of different neuroprotective drugs on dopamine neurotoxicity induced by 3,4-methylenedioxymethamphetamine and MPTP in mice
- Effect of crowding, temperature and age on glia activation and dopaminergic neurotoxicity induced by MDMA in the mouse brain.
- Repeated Administration of 3,4-Methylenedioxymethamphetamine (MDMA) Elevates the Levels of Neuronal Nitric Oxide Synthase in the Nigrostriatal System: Possible Relevance to Neurotoxicity
- Behavioral effects of psychostimulants in mutant mice with cell-type specific deletion of CB2 cannabinoid receptors in dopamine neurons
- Bath salts and polyconsumption: in search of drug-drug interactions
- Cannabinoids Δ9-tetrahydrocannabinol and cannabidiol may be effective against methamphetamine induced mitochondrial dysfunction and inflammation by modulation of Toll-like type-4(Toll-like 4) receptors and NF-κB signaling.
- Methamphetamine Blocks Adenosine A2A Receptor Activation via Sigma 1 and Cannabinoid CB1 Receptors
- Repeated exposure to JWH‐018 induces adaptive changes in the mesolimbic and mesocortical dopaminergic pathways, glial cells alterations, and behavioural correlates
- Co-exposure of cannabinoids with amphetamines and biological, behavioural and health outcomes: a scoping review of animal and human studies
- The Role of Hyperthermia in Methamphetamine-Induced Depression-Like Behaviors: Protective Effects of Coral Calcium Hydride
- MDMA related neuro-inflammation and adenosine receptors.
- Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice
- Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategies.
- Cannabis use may attenuate neurocognitive performance deficits resulting from methamphetamine use disorder
- Microglia in neuroimmunopharmacology and drug addiction
- Immune and glial cell alterations in the rat brain after repeated exposure to the synthetic cannabinoid JWH-018.
- Pharmacological Treatments for Methamphetamine Use Disorder: Current Status and Future Targets
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