WIP null mice display a progressive immunological disorder that resembles Wiskott–Aldrich syndrome
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Summary
It is shown that, in WIP null (WIP−/−) mice, it produces haematological alterations and anatomical abnormalities in several organs, most probably as a consequence of autoimmune attacks.
- Type
- article
- Published
- 2007-01-01
- Cited by
- 41
- References
- 34
- OpenAlex
- https://openalex.org/W2012188138
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:37117552
Keywords
Wiskott–Aldrich syndrome protein, Granulocytosis, Wiskott–Aldrich syndrome, Biology, Immunology
References
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- Mechanisms of WASp-mediated hematologic and immunologic disease.
Cited by
- Analysis of the domain specific function of the Wiskott Aldrich Syndrome Protein, in vitro and in vivo
- Prospects and perspectives on IgA nephropathy from animal models.
- Inhibiting Wipf2 downregulation by transgenic expression of its 3′ mRNA‐untranslated region improves cytotoxicity and vaccination response
- Role of PTEN in the Tumor Microenvironment
- Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells
- Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP.
- Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes.
- The Wiskott–Aldrich syndrome: from genotype–phenotype correlation to treatment
- WIP Regulates Persistence of Cell Migration and Ruffle Formation in Both Mesenchymal and Amoeboid Modes of Motility
- WIP Remodeling Actin behind the Scenes: How WIP Reshapes Immune and Other Functions
- WASP-interacting protein (WIP): working in polymerisation and much more.
- Cracking the platelet WIP.
- WIP, What an Interesting Protein for leukocyte activation, migration and inflammation
- WIP: more than a WASp‐interacting protein
- WASPs and WAVEs: from molecular function to physiology in hematopoietic cells.
- Primary immunodeficiencies: a rapidly evolving story.
- Immune Pathology Associated with Altered Actin Cytoskeleton Regulation
- An expression module of WIPF1-coexpressed genes identifies patients with favorable prognosis in three tumor types
- WIP is a negative regulator of neuronal maturation and synaptic activity.
- IDENTIFICATION AND CHARACTERIZATION OF WASP AND FKBP-LIKE PROTEIN
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