Analysis of mammalian origin specification in ORC-depleted Xenopus egg extracts.
Explore this paper's citation graph
Summary
It is concluded that a modification of Chinese Hamster chromatin takes place shortly after metaphase that complements a lack of XORC activity and represents an interaction of mammalian ORC with chromatin that is required for replication but, that is not sufficient for origin specification.
- Type
- article
- Published
- 1998-11-01
- Cited by
- 19
- References
- 47
- OpenAlex
- https://openalex.org/W2011737256
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10978244
Keywords
Xenopus, Biology, Chinese hamster ovary cell, Chromatin, Cell biology
References
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.
- Defining origins of replication in mammalian cells.
- Utilization of the same DNA replication origin by human cells of different derivation.
- The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin.
- Replicator renaissance
- Genes to cells: edited by Jun-ichi Tomizawa, Blackwell Science Ltd. Institutional: £218.00 (Europe), £242.00 (Rest of World), US382.00 (USA and Canada). Individual: £65.00 (Europe), £72.00 (Rest of World), US114.00 (USA and Canada) ISSN 1356 9597
- Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryos.
- Metaphase chromosome analysis by ligation-mediated PCR: heritable chromatin structure and a comparison of active and inactive X chromosomes.
- Cell Cycle Control of DNA Replication
- Origin-specific initiation of mammalian nuclear DNA replication in a Xenopus cell-free system.
- Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S. cerevisiae.
- Displacement of sequence-specific transcription factors from mitotic chromatin.
- Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes.
- Role for a Xenopus Orc2-related protein in controlling DNA replication
- DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts.
- A Distinct G1 Step Required to Specify the Chinese Hamster DHFR Replication Origin
- The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts.
- Conserved Initiator Proteins in Eukaryotes
- Identification of a Preinitiation Step in DNA Replication That Is Independent of Origin Recognition Complex and cdc6, but Dependent on cdk2
- Replication origins in yeast versus metazoa: separation of the haves and the have nots.
Cited by
- Is DNA sequence sufficient to specify DNA replication origins in metazoan cells?
- The role of protein kinases in DNA replication in Saccharomyces cerevisiae
- Mammalian nuclei become licensed for DNA replication during late telophase.
- Ubiquitylation, phosphorylation and Orc2 modulate the subcellular location of Orc1 and prevent it from inducing apoptosis
- Cell cycle‐dependent regulation of the association between origin recognition proteins and somatic cell chromatin
- Cell Cycle Dependent Regulation of the Origin Recognition Complex
- Review: nuclear structure and DNA replication.
- Selective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M–G1 transition in mammals
- Initiation of DNA replication in multicellular eukaryotes.
- Regulating the licensing of DNA replication origins in metazoa.
- Stability, chromatin association and functional activity of mammalian pre‐replication complex proteins during the cell cycle
- Origin recognition complex binding to a metazoan replication origin.
- The 'ORC cycle': a novel pathway for regulating eukaryotic DNA replication.
- Mammalian Orc1 Protein Is Selectively Released from Chromatin and Ubiquitinated during the S-to-M Transition in the Cell Division Cycle
- Enigmatic variations: divergent modes of regulating eukaryotic DNA replication.
- Role for Cdk1 (Cdc2)/Cyclin A in Preventing the Mammalian Origin Recognition Complex's Largest Subunit (Orc1) from Binding to Chromatin during Mitosis
- Selective activation of pre-replication complexes in vitro at specific sites in mammalian nuclei.
- Replication initiation: implications in genome integrity
- DNA Replication in S. pombe
Related papers
- Effects of protease inhibitiors on early stages of meiosis in Xenopus laevis oocytes.
- Twin Formation in Xenopus laevis Eggs Centrifuged before First Cleavage : Developmental Biology
- INDUCTION AND DIFFERENTIATION, ANALYSIS USING CULTURED CELL DERIVED FROM XENOPUS LAEVIS : Developmental Biology
- Synthesis of plant proteins in heterologous systems: Xenopus laevis oocytes.
- A mutation that reduces nucleolar number in Xenopus laevis.
- Xenopus laevis : practical uses in cell and molecular biology
- THE ISOLATION OF NUCLEI FROM XENOPUS LAEVIS EMBRYONIC CELLS.
- Differential replication of circular DNA molecules co-injected into early Xenopus laevis embryos.
- Platinum compounds with anti-tumour activity.