EFFECTS OF 6‐HYDROXYDOPAMINE ON CATECHOLAMINE CONTAINING NEURONES IN THE RAT BRAIN
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Summary
The results are consistent with the evidence in the peripheral sympathetic nervous system that 6‐OHDA causes a selective destruction of adrenergic nerve endings and suggest that this compound may have a similar destructive effect on catecholamine neurones in the CNS.
- Type
- article
- Published
- 1970-02-01
- Cited by
- 623
- References
- 26
- OpenAlex
- https://openalex.org/W2011700580
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:37441191
Keywords
Hydroxydopamine, Dopamine, Endocrinology, Catecholamine, Internal medicine
References
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- Degeneration of adrenergic nerves produced by 6-hydroxydopamine.
- REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐I
- Protein measurement with the Folin phenol reagent.
- Kinetics of H3-norepinephrine accumulation into slices from different regions of the rat brain.
- The physiologic disposition and metabolism of norepinephrine in immunosympathectomized animals.
- A FURTHER STUDY OF THE DISTRIBUTION OF γ‐AMINOBUTYRIC ACID BETWEEN EXCITATORY AND INHIBITORY AXONS OF THE LOBSTER
- A simple and rapid method for injecting H3-norepinephrine into the lateral ventricle of the rat brain.
- Adrenal Tyrosine Hydroxylase: Compensatory Increase in Activity after Chemical Sympathectomy
- Effect of environmental temperature on the turnover of noradrenaline in hypothalamus and other areas of rat brain
- THE UPTAKE OF [3H]GABA BY SLICES OF RAT CEREBRAL CORTEX
- A fluorimetric method for the determination of dopamine (3-hydroxytyramine).
- Ascending Monoamine Neurons to the Telencephalon and Diencephalon
- Effects of 6-Hydroxydopamine on Noradrenaline-containing Neurones in the Rat Brain
- MICRODETERMINATION OF MONOAMINE OXIDASE AND 5‐HYDROXYTRYPTOPHAN DECARBOXYLASE ACTIVITIES IN NERVOUS TISSUES
- Microdetermination of catechol-O-methyl transferase in brain.
- 6-Hydroxy-dopamine induced degeneration of central monoamine neurons.
- PINEAL DOPA DECARBOXYLASE AND MONOAMINE OXIDASE ACTIVITIES AS RELATED TO THE MONOAMINE STORES
- Storage and synthesis of norepinephrine in the reserpine-treated rat brain.
- ANTAGONISM OF CERTAIN EFFECTS OF CATECHOLAMINE-DEPLETING AGENTS BY ANTIDEPRESSANT AND RELATED DRUGS.
Cited by
- The use of neurotoxins to characterize the rates and subcellular distributions of axonally transported dopamine-beta-hydroxylase, tyrosine hydroxylase and norepinephrine in the rat brain.
- Striatal monoamines and reserpine and chlorpromazine rigidity.
- Intra‐ and extraneuronal formation of the two major noradrenaline metabolites in the cns of rats
- Recovery of brain noradrenaline after 5,7-dihydroxytryptamine-induced axonal lesions in the rat
- Relationship of brain monoamine and locomotor activity in rats.
- Relationships between indices of behavioral asymmetries and neurochemical changes following mesencephalic 6-hydroxydopamine injections.
- Studies on the up regulation of alpha-adrenoceptors on rat hippocampal perikarya by chemical lesion of the median raphe nucleus.
- Dopamine in the visual cortex of the cat
- Effect of drugs on excitatory and inhibitory potentials inHelix aspersa
- Central effects of 6‐hydroxydopamine on the body temperature of the rat
- Adaptive changes in catecholamine receptors in the central nervous system.
- Perturbations du contrôle traductionnel et troubles cognitifs dans un modèle expérimental de la maladie de Parkinson : études de neuroprotection
- Participation of central norepinephrine in the development of two-kidney, one clip Goldblatt hypertension.
- Opiate receptor mechanisms.
- Zinc-dependent potassium channel modulation mediates neuronal apoptosis
- Increased p53 levels without caspase-3 activity and change of cell viability in 6-hydroxydopamine-treated CV1-P cells
- EFFECTS OF GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR (GDNF) ON STEM/PROGENITOR CELL PROLIFERATION AND DIFFERENTIATION
- Experimental models of Parkinson's disease: insights from many models.
- Mechanisms of oxygen reduction by hydroquinones
- Apomorphine: chemistry, pharmacology, biochemistry.
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