MicroRNAs and human diseases: diagnostic and therapeutic potential
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Summary
The present review will explore the current knowledge about the role of miRNAs in various human diseases, and focus on the emerging evidences demonstrating the potential of mi RNAs as novel biomarkers and the strategies to use them as therapeutic tools.
- Type
- review
- Published
- 2014-02-04
- Cited by
- 61
- References
- 118
- OpenAlex
- https://openalex.org/W2011615645
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16569430
Keywords
microRNA, Biology, Human genetics, Computational biology, Bioinformatics
References
- Modulation of immune responses following solid organ transplantation by microRNA
- Coordinate Changes in Myosin Heavy Chain Isoform Gene Expression Are Selectively Associated With Alterations in Dilated Cardiomyopathy Phenotype
- Oncomirs — microRNAs with a role in cancer
- Circulating MicroRNA as Biomarkers: An Update in Prostate Cancer
- Obesity as a medical problem
- Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
- microRNAs in hypertrophy and heart failure
- MicroRNAs and Cell Cycle Regulation
- microRNA Control of Lifespan and Metabolism
- MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets.
- GATA4 expression is primarily regulated via a miR-26b-dependent post-transcriptional mechanism during cardiac hypertrophy.
- MicroRNAs in lipid metabolism
- The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases
- Increased MicroRNA-146a Levels in Plasma of Patients with Newly Diagnosed Type 2 Diabetes Mellitus
- Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients
- Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice.
- MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
- microRNAs and muscle disorders
- Up-regulated expression of microRNA-143 in association with obesity in adipose tissue of mice fed high-fat diet.
- The utility of LNA in microRNA-based cancer diagnostics and therapeutics.
Cited by
- The carboxy-terminal domain of connexin 43 (CT-Cx43) modulates the expression of p53 by altering miR-125b expression in low-grade human breast cancers
- Knockdown of Mir-135b Sensitizes Colorectal Cancer Cells to Oxaliplatin-Induced Apoptosis Through Increase of FOXO1
- Inhibition of miR-146b expression increases radioiodine-sensitivity in poorly differential thyroid carcinoma via positively regulating NIS expression.
- MicroRNA expression in inflamed and noninflamed gingival tissues from Japanese patients.
- MicroRNA-363-mediated downregulation of S1PR1 suppresses the proliferation of hepatocellular carcinoma cells.
- Ribonucleic acid (RNA) biosynthesis in human cancer
- Cell-free nucleic acids as noninvasive biomarkers for colorectal cancer detection
- miR-1 and miR-133b Are Differentially Expressed in Patients with Recurrent Prostate Cancer
- Role of miR‐145 in human laryngeal squamous cell carcinoma
- Micro- and nano-structure based oligonucleotide sensors.
- Decrease of Let-7f in Low-Dose Metronomic Paclitaxel Chemotherapy Contributed to Upregulation of Thrombospondin-1 in Breast Cancer
- Expression and role of oncogenic miRNA-224 in esophageal squamous cell carcinoma
- The Role of MicroRNAs in Diabetic Complications—Special Emphasis on Wound Healing
- Increased argonaute 2 expression in gliomas and its association with tumor progression and poor prognosis.
- Development of a molecular tool for oral squamous cell carcinoma risk assessment using microrna markers
- MicroRNA deep sequencing reveals chamber-specific miR-208 family expression patterns in the human heart.
- microRNA-339-5p modulates Na+/I− symporter-mediated radioiodide uptake
- MicroRNAs as Salivary Markers for Periodontal Diseases: A New Diagnostic Approach?
- Endoplasmic reticulum stress related molecular mechanisms in nonalcoholic steatohepatitis.
- Post-transcriptional regulation of the tumor suppressor p53 by a novel miR-27a, with implications during hypoxia and tumorigenesis.
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