Isolation and characterization of autophagy‐defective mutants of Saccharomyces cerevisiae
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Summary
The results on the apg mutants suggest that autophagy via autophagic bodies is indispensable for protein degradation in the vacuoles under starvation conditions, and that at least 15 APG genes are involved inAutophagy in yeast.
- Type
- article
- Published
- 1993-10-25
- Cited by
- 1,746
- References
- 12
- Access
- Open access
- OpenAlex
- https://openalex.org/W2011580247
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:46017791
Keywords
Vacuole, Mutant, Complementation, Autophagy, Saccharomyces cerevisiae
References
- Multiple methods of visualizing the yeast vacuole permit evaluation of its morphology and inheritance during the cell cycle
- Yeast endocytosis assays.
- Lysosomal (vacuolar) proteinases of yeast are essential catalysts for protein degradation, differentiation, and cell survival.
- Structure and function of the yeast vacuolar membrane proton ATPase
- Structure, molecular genetics, and evolution of vacuolar H+-ATPases
- Glucagon-induced autophagy and proteolysis in rat liver: mediation by selective deprivation of intracellular amino acids.
- Endocytosis in yeast: several of the yeast secretory mutants are defective in endocytosis.
- Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway.
- Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction
- Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes
- Genetic Control of the Cell Division Cycle in Yeast: V. Genetic Analysis of cdc Mutants.
- Protease B of Saccharomyces cerevisiae: isolation and regulation of the PRB1 structural gene.
Cited by
- Biogenesis of the yeast vacuole (lysosome). The use of active-site mutants of proteinase yscA to determine the necessity of the enzyme for vacuolar proteinase maturation and proteinase yscB stability.
- Regulation of hepatic protein degradation.
- Autophagy: cerebral home cooking.
- The APG8/12-activating Enzyme APG7 Is Required for Proper Nutrient Recycling and Senescence in Arabidopsis thaliana *
- Cell-death alternative model organisms: why and which?
- Autophagy and aging--importance of amino acid levels.
- Atg17 regulates the magnitude of the autophagic response.
- Rôle du stress du réticulum endoplasmique et de l’autophagie dans la régulation des réponses immune et angiogénique activées par des stress ischémiques et inflammatoires dans l’épithélium rénal humain
- Growth Culture Conditions and Nutrient Signaling Modulating Yeast Chronological Longevity
- Roles of sterol glucosyltransferase and actin cytoskeleton in pexophagy of the methylotrophic yeast
- Chloroplast signaling and quality control.
- HSV-TK/GCV can induce cytotoxicity of retinoblastoma cells through autophagy inhibition by activating MAPK/ERK
- The Multivesicular Body and Autophagosome Pathways in Plants
- Diverse Functions of Autophagy in Liver Physiology and Liver Diseases
- Methods to Measure Autophagy in Cancer Metabolism.
- The Role of Autophagy in Drosophila Metamorphosis
- Genetic regulation of autophagic cell death in Drosophila melanogester
- Autophagy and aging: lessons from progeria models.
- Approaches to the study of Atg8-mediated membrane dynamics in vitro.
- Identification of Receptor-like Protein for Fructose-1,6-bisphosphatase on Yeast Vacuolar Membrane
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