The stationary phase model of aging in yeast for the study of oxidative stress and age-related neurodegeneration
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Summary
The potential importance of using S. cerevisiae as a model system with which to explore the molecular basis for neuronal alterations observed in normal brain aging as well as multiple age–related diseases of the CNS is highlighted.
- Type
- review
- Published
- 2004-01-01
- Cited by
- 70
- References
- 58
- OpenAlex
- https://openalex.org/W2010905227
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24996713
Keywords
Neurodegeneration, Oxidative stress, Biology, Brain aging, Neuroscience
References
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- Genomic Heterogeneity of DNA Repair
- Oxidative stress and aging: beyond correlation
- SOD2 functions downstream of Sch9 to extend longevity in yeast.
- Role of RAS2 in recovery from chronic stress: effect on yeast life span.
- The measurement of oxidative damage to DNA by HPLC and GC/MS techniques.
- Proteasome synthesis and assembly are required for survival during stationary phase.
- The proteasome in brain aging.
- Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells.
- The budding yeast, Saccharomyces cerevisiae, as a model for aging research: a critical review.
Cited by
- Ubiquitin sets the timer: impacts on aging and longevity
- Polyglutamine diseases (PolyQ): construction and characterization of yeast models
- Aging Research in Yeast
- Methionine Sulfoxide Reductase in Neurodegenerative Disease and Locomotor-Associated Dopamine Signaling
- Gpd1 Regulates the Activity of Tcp-1 and Heat Shock Response in Yeast Cells: Effect on Aggregation of Mutant Huntingtin
- RNA interference toward UMP1 induces proteasome inhibition in Saccharomyces cerevisiae: evidence for protein oxidation and autophagic cell death.
- Chronological lifespan extension by Ecl1 family proteins depends on Prr1 response regulator in fission yeast
- The Genetic Profiles of TIF1 and TIF2 Duplicate Genes
- NET amyloidogenic backbone in human activated neutrophils
- Preadaptation to efficient respiratory maintenance is essential both for maximal longevity and the retention of replicative potential in chronologically ageing yeast.
- Protein-RNA cross-linking in the ribosomes of yeast under oxidative stress.
- Transcriptional Regulation in Yeast during Diauxic Shift and Stationary Phase
- What really declines with age?
- The main actors involved in parasitization of Heliothis virescens larva
- Aggregation of PolyQ Proteins Is Increased upon Yeast Aging and Affected by Sir2 and Hsf1: Novel Quantitative Biochemical and Microscopic Assays
- Quick and reliable assessment of chronological life span in yeast cell populations by flow cytometry.
- Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins
- EOS1, whose deletion confers sensitivity to oxidative stress, is involved in N-glycosylation in Saccharomyces cerevisiae.
- hsf1+ extends chronological lifespan through Ecl1 family genes in fission yeast
- Replicative and Chronological Aging in Saccharomyces cerevisiae
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