Coronavirus genome: prediction of putative functional domains in the non-structural polyprotein by comparative amino acid sequence analysis.
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Summary
A partial tentative scheme for the functional organization and expression strategy of the non-structural polyproteins of IBV implies that, despite the general similarity to other positive strand RNA viruses, and particularly to potyviruses, coronaviruses possess a number of unique structural and functional features.
- Type
- article
- Published
- 1989-06-26
- Cited by
- 319
- References
- 44
- Access
- Open access
- OpenAlex
- https://openalex.org/W2009793519
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14071091
Keywords
Biology, Genome, Peptide sequence, Genetics, Sequence (biology)
References
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- An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences.
- Sequence homology of the yeast regulatory protein ADR1 with Xenopus transcription factor TFIIIA
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- A viral cleavage site cassette: identification of amino acid sequences required for tobacco etch virus polyprotein processing.
- The complete nucleotide sequence of the RNA coding for the primary translation product of foot and mouth disease virus.
- Finger proteins and DNA‐specific recognition: Distinct patterns of conserved amino acids suggest different evolutionary modes
- Completion of the sequence of the genome of the coronavirus avian infectious bronchitis virus.
- Tests for comparing related amino-acid sequences. Cytochrome c and cytochrome c 551 .
- A novel superfamily of nucleoside triphosphate-binding motif containing proteins which are probably involved in duplex unwinding in DNA and RNA replication and recombination
- Primary structure and gene organization of human hepatitis A virus.
- Nucleotide sequence and genetic organization of barley stripe mosaic virus RNA gamma.
- Picornaviral processing: Some new ideas
- Fingering too many proteins.
- Zinc fingers: gilt by association.
Cited by
- The polymerase gene of corona- and toroviruses: evidence for an evolutionary relationship.
- Characterization of a second cleavage site and demonstration of activity in trans by the papain-like proteinase of the murine coronavirus mouse hepatitis virus strain A59
- Structure and Dynamics of Sars Coronavirus Main Proteinase (MPRO)
- Processing of the MHV-A59 gene 1 polyprotein by the 3C-like proteinase.
- Maturation of the polymerase polyprotein of the coronavirus MHV strain JHM involves a cascade of proteolytic processing events.
- Regulation of mRNA 1 expression by the 5'-untranslated region (5'-UTR) of the coronavirus infectious bronchitis virus (IBV).
- A newly identified MHV-A59 ORF1a polypeptide p65 is temperature sensitive in two RNA negative mutants.
- The Coronavirus Replicase: Insights into a Sophisticated Enzyme Machinery
- Proteolytic processing of the polyprotein encoded by ORF1b of the coronavirus infectious bronchitis virus (IBV).
- Products of the polymerase-encoding region of the coronavirus IBV.
- Proteolytic processing of the arterivirus replicase.
- Viral and Cellular Proteins Involved in Coronavirus Replication
- Genetic determinants of virulence for the A59 and JHM strains of mouse hepatitis virus
- Coronavirus polyprotein processing.
- DEVELOPMENT OF MOLECULAR DIAGNOSTIC ASSAYS FOR EQUINE RESPIRATORY VIRUSES AND ANALYSIS OF THE ROLE OF EQUINE ARTERITIS VIRUS ENVELOPE PROTEINS IN THE EARLY EVENTS OF VIRUS ENTRY
- Murine coronavirus gene 1 polyprotein contains an autoproteolytic activity.
- The molecular biology of arteriviruses.
- Complete Genome Sequence of Transmissible Gastroenteritis Coronavirus PUR46-MAD Clone and Evolution of the Purdue Virus Cluster
- Genomic Organization, Biology, and Diagnosis of Taura Syndrome Virus and Yellowhead Virus of Penaeid Shrimp
- Proteolytic processing of the N-terminal region of the equine arteritis virus replicase.
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