The Prevention and Treatment of Missing Data in Clinical Trials
Explore this paper's citation graph
Summary
Methods for preventing missing data and, failing that, dealing with data that are missing in clinical trials are reviewed.
- Type
- article
- Published
- 2012-10-04
- Cited by
- 1,839
- References
- 142
- Access
- Open access
- OpenAlex
- https://openalex.org/W2009432182
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17157011
Keywords
Medicine, Missing data, Clinical trial, MEDLINE, Intensive care medicine
References
- Informative dropout in longitudinal data analysis (with discussion)
- Impact of Missing Data Due to Dropouts on Estimates of the Treatment Effect in a Ranomized Trial of Antiretroviral Therapy for HIV-Infected Individuals
- Theory Testing in a World of Constrained Research Design
- Responsible Research: A Systems Approach to Protecting Research Participants
- Applied Longitudinal Analysis
- The Common Structure of Statistical Models of Truncation, Sample Selection and Limited Dependent Variables and a Simple Estimator for Such Models
- Have last-observation-carried-forward analyses caused us to favour more toxic dementia therapies over less toxic alternatives? A systematic review
- A note about models for selectivity bias.
- Analysis of failure time data under competing censoring mechanisms
- Conservative prior distributions for variance parameters in hierarchical models
- Undue Inducement: Nonsense on Stilts?
- Time-to-event analyses for long-term treatments--the APPROVe trial.
- Limiting loss to follow-up in a multicenter randomized trial in orthopedic surgery.
- Longitudinal data analysis for discrete and continuous outcomes.
- Maximum Likelihood Approaches to Variance Component Estimation and to Related Problems
- Tools for Statistical Inference: Observed Data and Data Augmentation Methods
- Pattern-Mixture Models for Multivariate Incomplete Data
- Last Observation Carried Forward: A Crystal Ball?
- INFERENCE AND MISSING DATA
- Sample size calculation for complex clinical trials with survival endpoints.
Cited by
- A Comparison of Last Observation Carried Forward and Multiple Imputation in a Longitudinal Clinical Trial
- Guest Editor's Note: Missing Data—Moving Forward
- Differences in Reporting of Analyses in Internal Company Documents Versus Published Trial Reports: Comparisons in Industry-Sponsored Trials in Off-Label Uses of Gabapentin
- Reporting and handling missing values in clinical studies in intensive care units
- Predictors of Relapse in Problem Gambling: A Prospective Cohort Study
- Prospective EHR-Based Clinical Trials: The Challenge of Missing Data
- A Peer-Led HIV Mediation Adherence Intervention Targeting Adults Linked to Medical Care but without a Suppressed Viral Load
- Coronary Artery Bypass Grafting in Patients 50 Years or Younger: A Swedish Nationwide Cohort Study
- Analytical results in longitudinal studies depended on target of inference and assumed mechanism of attrition.
- Cell phone Intervention for You (CITY): A randomized, controlled trial of behavioral weight loss intervention for young adults using mobile technology
- Incidence, correlates, and significance of abnormal cardiac enzyme rises in patients treated with surgical or percutaneous based revascularisation: a substudy from the Synergy between Percutaneous Coronary Interventions with Taxus and Cardiac Surgery (SYNTAX) Trial.
- Modeling competence development in the presence of selection bias
- Cautions as Regulators Move to End Exclusive Reliance on Intention to Treat
- Weekend effect in non‐elective abdominal aortic aneurysm repair
- Statistical Methods for patient chemosensitivity prediction based on in vitro Dose-response Data and A Modified Expectation-maximization (EM) Algorithm for Regression Analysis of Data with Non-ignorable Non-response
- Regression modeling with missing outcomes : competing risks and longitudinal data
- Are all clinical trial sites created equal?
- The ATLAS ACS 2-TIMI 51 trial and the burden of missing data: (Anti-Xa Therapy to Lower Cardiovascular Events in Addition to Standard Therapy in Subjects With Acute Coronary Syndrome ACS 2-Thrombolysis In Myocardial Infarction 51).
- Internet Interventions for Hearing Loss : Examing rehabilitation, self-report measures and internet use for hearing-aid users
- A Review of Statistical Approaches for the Analysis of Data in Rheumatology
Related papers
- Genentech taps Affimed’s antibodies
- KOMPLIKASI REGIONAL ANESTESI PADA PEDIATRIK
- Enxerto livre de arteria epigastrica inferior: avaliacao hemodinamica e angiografica pre e pos-operatoria
- Cardiac retransplantation in children.
- PD-09.06: Third kidney transplants: surgical aspects
- Avaliacao hemodinamica sequencial em transplante de coracao
- Thoracoscopic discectomy and fusion in the treatment of spinal deformities
- [Hepatic retransplant and acute Budd Chiari syndrome. Case report].