The next wave in metabolome analysis.
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Summary
The research community must develop databases of metabolite concentrations in cells that are grown in several well-defined conditions if metabolomic data are to be integrated meaningfully with data from the other levels of functional-genomic analysis and to make a significant contribution to systems biology.
- Type
- review
- Published
- 2005-11-01
- Cited by
- 241
- References
- 22
- OpenAlex
- https://openalex.org/W2009365322
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:42468603
Keywords
Metabolomics, Metabolome, Functional genomics, Computational biology, Genomics
References
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- Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network.
- Chemical derivatization and mass spectral libraries in metabolic profiling by GC/MS and LC/MS/MS.
- Effect of Slow Growth on Metabolism of Escherichia coli, as Revealed by Global Metabolite Pool (“Metabolome”) Analysis
Cited by
- Software and Database Usage on Metabolomic Studies: Using XCMS on LC-MS Data Analysis -
- Metabolic networks in motion: 13C-based flux analysis
- Redox regulation and antioxidative defence in Arabidopsis leaves viewed from a systems biology perspective.
- 3D micropatternable hydrogel systems to examine crosstalk effects between mesenchymal stem cells, osteoblasts, and adipocytes
- Elucidating the mode-of-action of compounds from metabolite profiling studies.
- Metabonomics and systems biology.
- System-wide approaches to uncover Th2 cell lineage commitment
- Probing the proteome response to toluene exposure in Pseudomonas putida
- In-depth analysis of the purine biosynthetic pathway of Corynebacterium glutamicum : from local pathway analysis to global phenotype profiling
- Application and assessment of experimental methods to study the cytosolic primary metabolism of yeast
- Integrating thermodynamics-based modeling and quantitative experimental data for studying microbial metabolism
- Cell metabolism in response to biomaterial mechanics
- Metabolome Analysis: An Introduction
- Comparative evaluation of planktonic and biofilm modes of growth in salmonella typhimurium
- Benefits and Limitations of Infrared Technologies in Omics Research and Development of Natural Drugs and Pharmaceutical Products
- Metabolomics - new trends in life chemistry
- Charakterisierung tierischer Zellkulturen anhand einer Quantifizierung intrazellulärer Metaboliten aus dem Zentralstoffwechsel
- Perspectives of the metabolic engineering of terpenoid indole alkaloids in Catharanthus roseus hairy roots.
- Fusing prior knowledge with microbial metabolomics
- Statistical identification of metabolic reactions catalyzed by gene products of unknown function
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