Clinical outcome of patients with lymph node‐negative breast carcinoma who have sentinel lymph node micrometastases detected by immunohistochemistry
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Summary
The authors evaluated how detailed assessment of SLNs using immunohistochemistry (IHC) and serial sectioning would affect treatment decisions and outcomes in patients with breast carcinoma who had negative SLNs on standard hematoxylin and eosin staining.
- Type
- review
- Published
- 2005-04-15
- Cited by
- 69
- References
- 36
- Access
- Open access
- OpenAlex
- https://openalex.org/W2009260241
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43650237
Keywords
Medicine, H&E stain, Sentinel lymph node, Micrometastasis, Adjuvant therapy
References
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- Therapeutic implications of the sentinel lymph node in breast cancer.
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- Tumor‐related prognostic factors for breast cancer
- Occult axillary lymph node metastases in "node-negative" breast carcinoma.
- Occult axillary node metastases in breast cancer: their detection and prognostic significance.
- Micrometastases to axillary lymph nodes from carcinoma of breast: detection by immunohistochemistry and prognostic significance.
- Micro-metastases in axillary lymph nodes: an increasing classification and treatment dilemma in breast cancer due to the introduction of the sentinel lymph node procedure
- Pathologic analysis of sentinel lymph nodes.
- Recommendations for Sentinel Lymph Node Processing in Breast Cancer
- Metastases in axillary sentinel lymph nodes in breast cancer as detected by intensive histopathological work up.
- Prospective identification of tumorigenic breast cancer cells
- Optimal histopathologic examination of the sentinel lymph node for breast carcinoma staging.
- Multiple sectioning and immunohistochemical staining of sentinel nodes in patients with breast cancer
Cited by
- Regional lymph node metastases; a singular manifestation of the process of clinical metastases in cancer: contemporary animal research and clinical reports suggest unifying concepts.
- Pathologic evaluation of axillary dissection specimens following unexpected identification of tumor within sentinel lymph nodes.
- Regional Management of Breast Cancer
- Lymphatic mapping/sentinel lymphadenectomy.
- Prediction of nonsentinel lymph node metastasis in sentinel node-positive breast carcinoma.
- Clinical Implications of Occult Metastases and Isolated Tumor Cells in Sentinel and Non-Sentinel Lymph Nodes in Early Breast Cancer Patients: Serial Step Section Analysis with Long-Term Follow-Up
- Intraoperative immunohistochemistry staining of sentinel nodes in breast cancer: clinical and economical implications.
- Sentinel node biopsy alone for node-positive breast cancer: 12-year experience at a single institution.
- Histopathologic characteristics of the primary tumor in breast cancer patients with isolated tumor cells of the sentinel node.
- Quantitative expression study of four cytokeratins and p63 in squamous cell carcinoma of the tongue: suitability for sentinel node navigation surgery using one-step nucleic acid amplification
- Re-evaluation of Axillary Skip Metastases in the Era of Sentinel Lymph Node Biopsy in Breast Cancer
- Sentinel node positive breast cancer patients who do not undergo axillary dissection: are they different?
- Validation and Limitations of Use of a Breast Cancer Nomogram Predicting the Likelihood of Non–Sentinel Node Involvement After Positive Sentinel Node Biopsy
- Clinical significance and management of sentinel node micrometastasis in invasive breast cancer.
- Sentinel lymph node evaluations.
- Are we wasting our time with the sentinel technique? Fifteen reasons to stop axilla dissection.
- Axillary lymph node dissection for sentinel lymph node micrometastases may be safely omitted in early-stage breast cancer patients: long-term outcomes of a prospective study
- The identification and treatment of isolated tumor cells reflect disparities in the delivery of breast cancer care.
- Determination of sentinel lymph node (SLN) status in primary breast cancer by prospective use of immunohistochemistry increases the rate of micrometastases and isolated tumour cells: analysis of 174 patients after SLN biopsy.
- Clinical significance of minimal sentinel node involvement and management options.
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