Studies on prostatic cancer. I. The effect of castration, of estrogen and androgen injection on serum phosphatases in metastatic carcinoma of the prostate.
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Summary
It is demonstrated that the acid phosphatase of serum is reduced in metastatic carcinoma of the prostate by decreasing the activity of androgens through castration or estrogenic injections and that this enzyme is increased by injecting androgens.
- Type
- article
- Published
- 1941-04-01
- Cited by
- 4,386
- References
- 14
- Access
- Open access
- OpenAlex
- https://openalex.org/W2008549629
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19786742
Keywords
Medicine, Castration, Estrogen, Prostate cancer, Cancer
References
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- The phosphatase activity of spleen extracts.
- The Possible Significance of Hexosephosphoric Esters in Ossification.
- Plasma Phosphatase in Osteitis Deformans and in other Diseases of Bone
- Significance of Increased Phosphatase Activity of Bone at the Site of Osteoplastic Metastases Secondary to Carcinoma of the Prostate Gland
- SOME EFFECTS OF SYNTHETICALLY PREPARED MALE HORMONE (ANDROSTERONE) IN THE RAT12
- AN " ACID " PHOSPHATASE OCCURRING IN THE SERUM OF PATIENTS WITH METASTASIZING CARCINOMA OF THE PROSTATE GLAND.
- “Acid” Phosphatase and Functional Activity of the Prostate (Man) and Preputial Glands (Rat)
- Clinical Significance of Increased Serum “ACID” Phosphatase in Patients with Bone Metastases Secondary to Prostatic Carcinoma
Cited by
- Pre-estrogen breast irradiation for patients with carcinoma of the prostate: a critical review.
- Prognostic factors for survival of patients with bidimensionally measurable metastatic hormone‐refractory prostatic cancer treated with single‐agent chemotherapy
- Long-Term Results with the Gn-Rh Analogue, Buserelin, in Metastatic Prostate Cancer
- Molecular cloning of cDNA for human prostatic acid phosphatase.
- Genitourinary‐Tract Problems of the Aged Male *
- Complications and regression of primary tumor size with radiotherapy in prostatic cancer.
- Androgens and prostate‐specific acid phosphatase in whole tissue and in separated epithelium from human benign prostatic hypertrophic glands
- Physicochemical characterization of the androgen receptor from hyperplastic human prostate
- Prostate specific antigen decline following the discontinuation of flutamide in patients with stage D2 prostate cancer.
- Gonadotropin-releasing hormone antagonist in the management of prostate cancer.
- Blockade of androstenedione-induced stimulation of androgen-sensitive parameters in the rat prostate by combination of Flutamide and 4-MA.
- Peptide analogs in the therapy of prostate cancer
- Antiandrogen Withdrawal Syndrome Associated with Prostate Cancer Therapies
- [Suppressive effects of the antiandrogen flutamide on adrenal androgens in advanced prostate cancer patients].
- Quercetin inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells.
- Assessing the effect of fatty acids on prostate carcinogenesis in humans: does self-reported dietary intake rank prostatic exposure correctly?
- Does physical activity play a role in the prevention of prostate cancer?
- The role of hormonal treatment in prostate cancer.
- MicroPET assessment of androgenic control of glucose and acetate uptake in the rat prostate and a prostate cancer tumor model.
- 3β-Acetoxyandrost-1,5-diene-17-ethylene ketal functions as a potent antiandrogen with marginal agonist activity
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