Animal Models of Neuropsychiatric Disorders
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Summary
The current state of animal models of mental illness, with a focus on schizophrenia, depression and bipolar disorder, is reviewed and it is argued for areas of focus that might increase the likelihood of creating more useful models, at least for some disorders.
- Type
- review
- Published
- 2010-09-27
- Cited by
- 2,065
- References
- 74
- Access
- Open access
- OpenAlex
- https://openalex.org/W2007816528
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2175644
Keywords
Schizophrenia (object-oriented programming), Bipolar disorder, Neuroscience, Psychology, Animal model
References
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- Relevance of Transgenic Mouse Models to Human Alzheimer Disease*
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- 2q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia
- Acute hippocampal BDNF restores motivational and forced swim performance after corticosterone
- Intracranial self-stimulation (ICSS) in rodents to study the neurobiology of motivation
- Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
- Reverse translational strategies for developing animal models of bipolar disorder
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- Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia
Cited by
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- 5-HT2 ligands in the treatment of anxiety and depression
- Lamotrigine positively affects the development of psychiatric comorbidity in epileptic animals, while psychiatric comorbidity aggravates seizures.
- Stress and Drug Dependence Differentially Modulate Norepinephrine Signaling in Animals with Varied HPA Axis Function
- Heart rate variability in animal models of psychological-cardiovascular comorbidity
- Pervasive and opposing effects of Unpredictable Chronic Mild Stress (UCMS) on hippocampal gene expression in BALB/cJ and C57BL/6J mouse strains
- Mice lacking circadian clock components display different mood-related behaviors and do not respond uniformly to chronic lithium treatment
- Modeling Psychiatric Disorders with Patient-derived iPSCs
- Advances in Nonhuman Primate Models of Autism: Integrating Neuroscience and Behavior
- Compartmentalized devices as tools for investigation of human brain network dynamics
- Orexin 2 receptor stimulation enhances resilience, while orexin 2 inhibition promotes susceptibility, to social stress, anxiety and depression
- Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background
- The Forced Swim Test for Depression-Like Behavior in Rodents.
- A framework for the ethical assessment of chimeric animal research involving human neural tissue
- Sexual Reward and Depression
- Beyond neurons: The role of the oligodendrocyte-specific gene CNP1 in major depressive disorder
- Impaired performance on touchscreen object-location paired associates learning by acute systemic MK-801 is reversed by L-govadine but not D-govadine or CDPPB
- Animal Models of Depression: Molecular Perspectives
- Characterization of the Rho-GEF Kalirin-7 in the Mouse Brain: Evidence for a Role in Learning and Addictive-Like Behaviors, as Well as Neuronal Morphology and NMDA Receptor Signaling.
- Does Time Really Tell All? The Effect of Circadian Rhythms on Emotional-like Behavior in Rats Selectively Bred to Model Mood Disorders
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