Angiotensin-Converting Enzyme Inhibition Increases Human Vascular Tissue-Type Plasminogen Activator Release Through Endogenous Bradykinin
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Summary
Enalaprilat increased the t-PA response to bradykinin to a greater extent than the FBF response, shifting the relationship between net t- PA release and FBF (P =0.005).
- Type
- article
- Published
- 2003-02-04
- Cited by
- 105
- References
- 37
- Access
- Open access
- OpenAlex
- https://openalex.org/W2007129904
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2890045
Keywords
Enalaprilat, Bradykinin, Endocrinology, Internal medicine, Medicine
References
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- Comparative Effects of Estrogen and Angiotensin-Converting Enzyme Inhibition on Plasminogen Activator Inhibitor-1 in Healthy Postmenopausal Women
- An Endothelial Storage Granule for Tissue-Type Plasminogen Activator
- Effects of ramipril on plasma fibrinolytic balance in patients with acute anterior myocardial infarction. HEART Study Investigators.
- Ramipril prevents major cardiovascular events in high-risk women: results of the HOPE trial
- The effects of the angiotensin-converting enzyme inhibitor imidapril on plasma plasminogen activator inhibitor activity in patients with acute myocardial infarction.
- Comparison of cholinergic vasodilator responses to acetylcholine and methacholine in the human forearm.
- Role of bradykinin in the vasodilator effects of losartan and enalapril in patients with heart failure.
- Clearance of tissue plasminogen activator (TPA) and TPA/plasminogen activator inhibitor type 1 (PAI-1) complex: relationship to elevated TPA antigen in patients with high PAI-1 activity levels.
- Human coronary arteriolar dilation to bradykinin depends on membrane hyperpolarization: contribution of nitric oxide and Ca2+-activated K+ channels.
- Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors.
- 17Beta-estradiol acutely improves endothelium-dependent relaxation to bradykinin in isolated human coronary arteries.
- Impaired endothelium-dependent vasodilation in patients with essential hypertension. Evidence that nitric oxide abnormality is not localized to a single signal transduction pathway.
- Captopril improves impaired endothelium-dependent vasodilation in hypertensive patients.
- Cough and Angioneurotic Edema Associated with Angiotensin-Converting Enzyme Inhibitor Therapy
- Fibrinolytic activity, clotting factors, and long-term incidence of ischaemic heart disease in the Northwick Park Heart Study.
- Endothelium-Dependent Vasodilation is Augmented by Angiotensin Converting Enzyme Inhibitors in Healthy Volunteers
- Acetylcholine-Mediated Vasodilatation and Tissue-type Plasminogen Activator Release in Normal and Hypertensive Men
- Inositol trisphosphate/Ca2+ as messengers of bradykinin B2 and muscarinic acetylcholine m1-m4 receptors in neuroblastoma-derived hybrid cells.
Cited by
- Inhibition of RAAS—When is it too much?
- INFLAMACIÓN Y TROMBOSIS: DEL LABORATORIO A LA CLÍNICA
- Impairment of Endothelial Thromboprotective Function by Haemodynamic and Inflammatory Stress Implications for hypertensive disease
- Regulation of Kinin Receptor Expression in Heart Failure with a Focus on Vascular Endothelium
- Carvedilol‐Lisinopril Combination Therapy and Endothelial Function in Obese Individuals With Hypertension
- Plasma Plasminogen Activator Inhibitor 1 (PAI-1) and p-Selectin Levels in Urgent Hypertension: Effect of Single Dose Captopril and Nifedipin on Fibrinolytic Activity
- Angiotensin-converting enzyme inhibition alters the inflammatory and fibrinolytic response to cardiopulmonary bypass in children*
- The kallikrein-kinin system: current and future pharmacological targets.
- Met-Lys-bradykinin-Ser-Ser, a peptide produced by the neutrophil from kininogen, is metabolically activated by angiotensin converting enzyme in vascular tissue.
- Impact of kinins in the treatment of cardiovascular diseases.
- The prothrombotic paradox of hypertension: role of the renin-angiotensin and kallikrein-kinin systems.
- Vascular injury in systemic sclerosis: Angiotensin-converting enzyme insertion/deletion polymorphism
- ACE inhibition reduces activity of the plasminogen/plasmin and MMP systems in the brain of spontaneous hypertensive stroke-prone rats.
- Kinins and cardiovascular diseases.
- An in vitro reconstitution system to address the mechanism of the vascular expression of the bradykinin B₁ receptor in response to angiotensin converting enzyme inhibition.
- Microvascular tissue plasminogen activator is reduced in diabetic neuropathy
- Effects of Losartan and Delapril on the Fibrinolytic System in Patients with Mild to Moderate Hypertension
- Low HDL Cholesterol, Smoking and IL-13 R130Q Polymorphism are Associated with Myocardial Infarction in Greek Cypriot Males. A Pilot Study
- NO-Dependent Endothelial Dysfunction in Type II Diabetes Is Aggravated by Dyslipidemia and Hypertension, but Can Be Restored by Angiotensin-Converting Enzyme Inhibition and Weight Loss
- Impaired fibrinolysis in retinal vein occlusion: a role for genetic determinants of PAI-1 levels
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