Negatively charged amino acid residues in the nicotinic receptor delta subunit that contribute to the binding of acetylcholine.

Keywords

Acetylcholine receptor, Acetylcholine, Nicotinic acetylcholine receptor, Nicotinic agonist, Binding site

References

• Mutations affecting agonist sensitivity of the nicotinic acetylcholine receptor.Gordon F. Tomaselli, James T. McLaughlin, Mark E. Jurman — 1991
• Mapping and modification of an antibody hapten binding site: a site-directed mutagenesis study of McPC603.Rudi Glockshuber, Joerg Stadlmueller, A. Plueckthun — 1991

Cited by

• Nicotinic acetylcholine receptor-lipid interactions: Mechanistic insight and biological function.Audra Ayu O., Vincensia Dyan Aryati — 2015
• Structure-Function Studies of Nicotinic Acetylcholine Receptors Using Unnatural Amino Acids and Synthetic Agonist AnalogsAngela P. Blum — 2012
• Structure-function studies of nicotinic acetylcholine receptors using unnatural amino acidsNyssa L. Puskar — 2012
• Evidence for an Extended Hydrogen Bond Network in the Binding Site of the Nicotinic ReceptorAngela P. Blum, Kristin Rule Gleitsman, Henry A. Lester — 2011
• Mapping the agonist binding site of the GABAA receptor: evidence for a beta-strand.Andrew J. Boileau, Amy R. Evers, Anson F. Davis — 1999
• Neuronal nicotinic acetylcholine receptors.Jon Lindstrom — 1996
• The emerging three-dimensional structure of a receptor. The nicotinic acetylcholine receptor.Ferdinand Hucho, Victor I. Tsetlin, Jan Machold — 1996
• Determinants of Competitive Antagonist Sensitivity on Neuronal Nicotinic Receptor β SubunitsScott C. Harvey, Charles W. Luetje — 1996
• Identification of Transduction Elements for Benzodiazepine Modulation of the GABAA Receptor: Three Residues Are Required for Allosteric CouplingAndrew J. Boileau, Cynthia Czajkowski — 1999
• Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptorsKatjuša Brejc, Willem J. van Dijk, Remco V. Klaassen — 2001
• Heritable mutations in the glycine, GABAA, and nicotinic acetylcholine receptors provide new insights into the ligand-gated ion channel receptor superfamily.Behnaz Vafa, Peter R. Schofield — 1998
• Determinants of Agonist Binding Affinity on Neuronal Nicotinic Receptor β SubunitsMichael Parker, Simon C. Harvey, Charles W. Luetje — 2001
• How do acetylcholine receptor ligands reach their binding sites?Patricio Sáez‐Briones, M. Krauß, Mathias Dreger — 1999
• Potentiation of Acetylcholine Receptors by Divalent CationsJon Lindstrom — 2006
• Structure of the Nicotinic Receptor Acetylcholine-binding SiteCynthia Czajkowski, Arthur Karlin — 1995
• Caenorhabditis elegans Levamisole Resistance Geneslev-1, unc-29, and unc-38 Encode Functional Nicotinic Acetylcholine Receptor SubunitsJohn T. Fleming, Michael D. Squire, Thomas M. Barnes — 1997
• Neuromuscular Activity of Micrurus laticollaris (Squamata: Elapidae) Venom in VitroAlejandro Carbajal‐Saucedo, Rafael Stuani Floriano, Cháriston André Dal Belo — 2014
• Structure – activity relationships of nicotinic acetylcholine receptor agonists as potential treatments for dementiaMark W. Holladay, Suzanne A. Lebold, Nan‐Horng Lin — 1995
• The histrionicotoxin-sensitive ethidium binding site is located outside of the transmembrane domain of the nicotinic acetylcholine receptor: a fluorescence study.David A. Johnson, John M. Nuss — 1994
• Role of loop 9 on the function of neuronal nicotinic receptors.Manuel Criado, Mar Castillo, José Mulet — 2010

Related papers

• Nicotinic acetylcholine receptor is involved in acetylcholine regulating stomatal movementHengbin Wang, Xuechen Wang, Shuqiu Zhang — 1998
• Irreversible inhibition of nicotinic acetylcholine receptors by the bipinnatins. Toxin activation and kinetics of receptor inhibition.Duncan R. Groebe, J.M. Dumm, Stewart N. Abramson — 1994
• Functional diversity of neuronal nicotinic acetylcholine receptors.Jim Patrick, Philippe Séquéla, Steven Vernino — 1993
• Functional Domains of the Nicotinic Acetylcholine Receptor aArthur Karlin, Robert N. Cox, Mario DiPaola — 1986
• Nicotinic acetylcholine receptor : structure and functionAlfred Maelicke — 1986
• Identification of a cytoplasmic region of the Torpedo nicotinic acetylcholine receptor alpha-subunit by epitope mapping.Steen E. Pedersen, Paul C. Bridgman, Sheila Sharp — 1990
• Mapping of a binding site for ATP within the extracellular region of the Torpedo nicotinic acetylcholine receptor beta-subunit.André Schrattenholz, Uli Roth, Jasminka Godovac‐Zimmermann — 1997
• Evidence that porcine native 5-HT3 receptors do not contain nicotinic acetylcholine receptor subunits.Stephanie Fletcher, Jon Lindstrom, Ruth M. McKernan — 1998