Continuously growing bipotential and monopotential myogenic, adipogenic, and chondrogenic subclones isolated from the multipotential RCJ 3.1 clonal cell line.
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Summary
The clonal multipotential RCJ 3.1 cell line, which gives rise to myotubes, adipocytes, chondrocytes, and osteoblasts, contains different progenitor subpopulations which provide a valuable model for studying the mechanisms leading to lineage restriction in mesenchymal populations.
- Type
- article
- Published
- 1990-12-01
- Cited by
- 110
- References
- 14
- OpenAlex
- https://openalex.org/W2005151588
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24646126
Keywords
Biology, Myogenesis, Progenitor cell, Cell biology, Cell culture
References
- Precursor cells of mechanocytes.
- Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine.
- A STOCHASTIC MODEL OF STEM CELL PROLIFERATION, BASED ON THE GROWTH OF SPLEEN COLONY-FORMING CELLS.
- Single cell origin of multilineage colonies in culture. Evidence that differentiation of multipotent progenitors and restriction of proliferative potential of monopotent progenitors are stochastic processes.
- Isolation of bone cell clones with differences in growth, hormone responses, and extracellular matrix production
- Differentiation in mouse melanoma cells: initial reversibility and an on-off stochastic model.
- Single-cell origin of mouse hemopoietic colonies expressing multiple lineages in variable combinations.
- Changes in phenotypic expression in embryonic and adult cells treated with 5‐azacytidine
- Hemopoietic stem cell differentiation.
- Flexible association of hemopoietic differentiation programs in multilineage colonies
- 5-Azacytidine induction of stable mesodermal stem cell lineages from 10T1/2 cells: evidence for regulatory genes controlling determination.
- Effects of dexamethasone and vitamin D3 on cartilage differentiation in a clonal chondrogenic cell population.
- Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone
- A stochastic model of self‐renewal and commitment to differentiation of the primitive hemopoietic stem cells in culture
Cited by
- Surface adhesion‐mediated regulation of chondrocyte‐specific gene expression in the nontransformed RCJ 3.1c5.18 rat chondrocyte cell line
- Fibroblast growth factor receptor 3 gene: regulation by serum response factor.
- Inhibition of Wnt/β-catenin signaling by dexamethasone promotes adipocyte differentiation in mesenchymal progenitor cells, ROB-C26
- Glucose transport and metabolism in chondrocytes: a key to understanding chondrogenesis, skeletal development and cartilage degradation in osteoarthritis.
- In vitro 軟骨分化モデルの構築と解析
- In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells.
- The behavior of rotator cuff tendon cells in three-dimensional culture
- BMPs and the muscle-bone connection.
- Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage [published erratum appears in J Cell Biol 1995 Feb;128(4):following 713]
- Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor
- Osteoclast differentiation in cocultures of a clonal chondrogenic cell line and mouse bone marrow cells.
- Isolation of Markers for Chondro-osteogenic Differentiation Using cDNA Library Subtraction
- Antiproliferative Effects of Insulin-like Growth Factor-binding Protein-3 in Mesenchymal Chondrogenic Cell Line RCJ3.1C5.18
- Glucocorticoids induce the differentiation of a mesenchymal progenitor cell line, ROB-C26 into adipocytes and osteoblasts, but fail to induce terminal osteoblast differentiation.
- EXPRESSION OF CATION EXCHANGER NHE AND ANION EXCHANGER AE ISOFORMS IN PRIMARY HUMAN BONE‐DERIVED OSTEOBLASTS
- A new synthetic compound, SST-VEDI-1, inhibits osteoblast differentiation with a down-regulation of the Osterix expression.
- A novel insulin-like growth factor (IGF)-independent role for IGF binding protein-3 in mesenchymal chondroprogenitor cell apoptosis.
- Chondrogenic differentiation of murine embryonic stem cells: Effects of culture conditions and dexamethasone
- The Frequency of Common Progenitors for Adipocytes and Osteoblasts and of Committed and Restricted Adipocyte and Osteoblast Progenitors in Fetal Rat Calvaria Cell Populations *
- Flexible and dynamic organization of bone marrow stromal compartment
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