The Structure of an Infectious P22 Virion Shows the Signal for Headful DNA Packaging

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Summary

A 17 angstrom resolution asymmetric reconstruction of the infectious P22 virion reveals that tightly spooled DNA about the portal dodecamer forces a conformation that is significantly different from that observed in isolated portals assembled from ectopically expressed protein.

Type
article
Published
2006-06-23
Cited by
320
References
22

Keywords

Capsid, DNA, Dodecameric protein, Structural protein, Rolling circle replication

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