Defective mismatch-repair as a minor tumorigenic pathway in Barrett esophagus-associated adenocarcinoma.

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Summary

The findings suggest that only a small subset of Barrett adenocarcinomas develop because of defective MMR, but demonstrate that MLH1 and MSH2 are the primary targets for defective MMR also in this tumor type.

Type
article
Published
2005-02-01
Cited by
23
References
18

Keywords

MSH2, MLH1, Microsatellite instability, DNA mismatch repair, Biology

References

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