Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family.

Explore this paper's citation graph

Summary

These findings strongly implicate Spo11 as the catalytic subunit of the meiotic DNA cleavage activity and provide direct evidence that the mechanism of meiotic recombination initiation is evolutionarily conserved.

Type
article
Published
1997-02-07
Cited by
1,859
References
59
Access
Open access

Keywords

Biology, Schizosaccharomyces pombe, Homologous recombination, Saccharomyces cerevisiae, Genetics

References

Cited by

Related papers