Racial differences in response to therapy for heart failure: analysis of the vasodilator-heart failure trials. Vasodilator-Heart Failure Trial Study Group.
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Summary
Wales and blacks showed differences in cause, neurohormonal stimulation, and pharmacological response in heart failure, and angiotensin-converting enzyme inhibitors are particularly effective in whites and the H-I combination can be equally effective in blacks.
- Type
- article
- Published
- 1999-09-01
- Cited by
- 489
- References
- 30
- OpenAlex
- https://openalex.org/W2001323802
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:30813727
Keywords
Medicine, Isosorbide dinitrate, Heart failure, Internal medicine, Cardiology
References
- Influence of prerandomization (baseline) variables on mortality and on the reduction of mortality by enalapril. Veterans Affairs Cooperative Study on Vasodilator Therapy of Heart Failure (V-HeFT II). V-HeFT VA Cooperative Studies Group.
- Ejection Fraction, Peak Exercise Oxygen Consumption, Cardiothoracic Ratio, Ventricular Arrhythmias, and Plasma Norepinephrine as Determinants of Prognosis in Heart Failure
- Plasma renin activity and plasma prorenin assays.
- The intravenous furosemide test: a simple way to evaluate renin responsiveness.
- Sodium and water balance in chronic congestive heart failure.
- Renin system activity as a determinant of response to treatment in hypertension and heart failure.
- Pathophysiology of Hypertension in Blacks and Whites: A Review of the Basis of Racial Blood Pressure Differences
- Trends in hospitalization rates for heart failure in the United States, 1973-1986. Evidence for increasing population prevalence.
- Hospitalization for congestive heart failure. Explaining racial differences.
- The interaction of norepinephrine excretion with blood pressure and race in children
- A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure.
- Cigarette smoking does not attenuate the cardiovascular effects of epoprostenol (prostacyclin) in humans.
- Racial differences in the outcome of left ventricular dysfunction.
- Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug.
- Precipitating factors leading to decompensation of heart failure. Traits among urban blacks.
- Edema of cardiac origin. Studies of body water and sodium, renal function, hemodynamic indexes, and plasma hormones in untreated congestive cardiac failure.
- A simplified radiometric assay for plasma norepinephrine and epinephrine.
- Prevention of tolerance to hemodynamic effects of nitrates with concomitant use of hydralazine in patients with chronic heart failure.
- Racial differences in response to low-dose captopril are abolished by the addition of hydrochlorothiazide.
- Concurrent Hydralazine Administration Prevents Nitroglycerin‐Induced Hemodynamic Tolerance in Experimental Heart Failure
Cited by
- Race/Ethnicity: Is it an Outcome Predictor in Patients with Heart Failure?
- Nitric oxide and vascular reactivity in African American patients with hypertension.
- Inhibition of RAAS—When is it too much?
- Into the fold
- Endothelial nitric oxide synthase (NOS3) polymorphisms in African Americans with heart failure: results from the A-HeFT trial.
- The A's, G's, C's, and T's of health disparities
- Association of race, heart failure and chronic kidney disease.
- Characteristics Associated with Racial Disparities in Illness Beliefs of Patients with Heart Failure
- The Antiplatelet Effects of Nitrates: Is it of Clinical Significance in Patients With Cardiovascular Disease?
- Outcomes and worsening renal function in patients hospitalized with heart failure with preserved ejection fraction.
- Heart failure: clinical problem and management issues.
- Racial Differences in Responses to Drug Treatment
- Arguing science, creating race: the 2005 FDA approval hearings for BiDil
- Pharmacologic management of heart failure caused by systolic dysfunction.
- Treatment of heart failure in African Americans--a call to action.
- Ethnic differences in endothelial function and monocyte subsets in heart failure
- Studies of the Epidemiology and Prognosis of Patients with Heart Failure in Leicestershire
- Heart failure therapy in special populations: the same or different?
- Foundations of Pharmacotherapy for Heart Failure With Reduced Ejection Fraction: Evidence Meets Practice, Part I
- Pericardial Effusion and Multiple Organ Involvement Are Independent Predictors of Mortality in Patients with Systemic Light Chain Amyloidosis.
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