Selective synthesis of α-fluoro-β-keto- and α-fluoro-β-aminophosphonates via electrophilic fluorination by selectfluor.
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Summary
Synthetic potential of the obtained α-mono- and α,α-difluoro-β-ketophosphonates was demonstrated by their application in synthesis ofα-monofluoro -β-aminophosph onates, useful building blocks in the preparation of phosphapeptides.
- Type
- article
- Published
- 2011-01-18
- Cited by
- 38
- References
- 1
- OpenAlex
- https://openalex.org/W2001318563
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21449031
Keywords
Selectfluor, Electrophilic fluorination, Chemistry, Electrophile, Organic chemistry
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Cited by
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- Selectfluor‐Mediated Fluorination and C–C Bond Cleavage of Cyclohexene‐Fused Isoxazoline N‐Oxides
- Synthesis of β-ketophosphonates via AgNO3-catalyzed hydration of alkynylphosphonates: a rate-enhancement effect of methanol
- Synthesis and spectral properties of α,α-difluorinated β-iminophosphonates
- Synthesis of N-substituted α,α-difluoro-β-aminophosphonates by addition of diethyl lithiodifluoromethylphosphonate to imines
- Asymmetric catalysis as a method for the synthesis of chiral organophosphorus compounds
- Copper/Iron-Catalyzed Aerobic Oxyphosphorylation of Terminal Alkynes Leading to β-Ketophosphonates.
- Copper-catalyzed oxidative esterification of unactivated C(sp3)–H bonds with carboxylic acids via cross dehydrogenative coupling
- Mono and difluorination of centers α to sulfonates and phosphonates using AcOF
- Recent advances in the synthesis of fluorinated aminophosphonates and aminophosphonic acids
- Monofluorination of Organic Compounds: 10 Years of Innovation.
- Reactions of propargyl compounds containing a cyclobutyl group induced by a ruthenium complex.
- An efficient difluorohydroxylation of indoles using selectfluor as a fluorinating reagent.
- Synthesis of Phosphorylated Enaminoketones and Their Application in the Preparation of Trifluoromethyl-Functionalized 2-Phosphonopyrroles
- Selective monofluorination of active methylene compounds: the important role of ZnCl2 in inhibiting overfluorination
- β-Ketophosphonates formation via deesterification or deamidation of cinnamyl/alkynyl carboxylates or amides with H-phosphonates
- Organocatalytic Asymmetric Michael Addition of α‐Fluoro β‐Ketophosphonate to Nitroalkenes
- A Reagent-Controlled Phospha-Michael Addition Reaction of Nitroalkenes with Bifunctional N-Heterocyclic Phosphine (NHP)-Thioureas.
- Cu(i)/Fe(iii)-Catalyzed C-P cross-coupling of styrenes with H-phosphine oxides: a facile and selective synthesis of alkenylphosphine oxides and β-ketophosphonates.
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