Therapeutics for Circadian Rhythm Sleep Disorders
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Summary
Timed administration of melatonin, either alone or in combination with light therapy has been shown to be useful in the treatment of the following circadian rhythm sleep disorders: delayed sleep phase, advanced sleep phase, free-running, irregular sleep wake, jet lag and shift work.
- Type
- article
- Published
- 2010-12-01
- Cited by
- 108
- References
- 124
- Access
- Open access
- OpenAlex
- https://openalex.org/W2001205462
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4589338
Keywords
Circadian rhythm, Free-running sleep, Light effects on circadian rhythm, Dark therapy, Phase response curve
References
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- Larger phase angle between sleep propensity and melatonin rhythms in sighted humans with non-24-hour sleep-wake syndrome.
- Modafinil improves alertness, vigilance, and executive function during simulated night shifts.
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- Phase-shifting effects of bright morning light as treatment for delayed sleep phase syndrome.
- Melantonin for the treatment of advanced sleep phase disorder.
- Dark goggles and bright light improve circadian rhythm adaptation to night-shift work.
- The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: assessment in a clinical trial of melatonin replacement.
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- Melatonin for the prevention and treatment of jet lag.
Cited by
- Region-specific effects of restricted feeding on daily rhythms of the clock proteins, Period1 and Period2, in the forebrain of the male Wistar rat
- Circadian Rhythm Abnormalities
- Lichttherapie: Zum Stand der aktuellen Forschung
- Synchrony and desynchrony in circadian clocks: impacts on learning and memory
- Trastornos del sueño en la adolescencia
- The melatonin receptor agonist is effective for free-running type circadian rhythm sleep disorder: case report on two sighted patients.
- Non-surgical periodontal therapy influences salivary melatonin levels
- Recommendations of the Sleep Study Group of the Italian Dementia Research Association (SINDem) on clinical assessment and management of sleep disorders in individuals with mild cognitive impairment and dementia: a clinical review
- Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances, but does not improve the sleeping problems
- Why the dim light melatonin onset (DLMO) should be measured before treatment of patients with circadian rhythm sleep disorders.
- Sick and Tired: How molecular regulators of human sleep schedules and duration impact immune function
- Tasimelteon: First Global Approval
- Sleep medicine pharmacotherapeutics overview: today, tomorrow, and the future (Part 1: insomnia and circadian rhythm disorders).
- Sleep medicine pharmacotherapeutics overview: today, tomorrow, and the future (part 2: hypersomnia, parasomnia, and movement disorders).
- Cell signaling, receptors, electrical effects and therapy in circadian rhythm
- Selective targets for arousal-modifying drugs: implications for the treatment of sleep disorders.
- Shift Work Sleep Disorder and Complications
- Genetic Insights on Sleep Schedules: This Time, It’s PERsonal
- Insomnia and shift-work sleep disorder: A crosstalk between glutamate excitotoxicity and decreased GABAergic neurotransmission?
- Relevance of Chronobiology to the Research and Clinical Practice of Neurorehabilitation
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