Serum concentrations of opioids when comparing two switching strategies to methadone for cancer pain
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Summary
The SAG group was initially more exposed to methadone and less to the replaced opioids but without observed clinical benefit and with a higher dropout rate.
- Type
- article
- Published
- 2012-02-29
- Cited by
- 13
- References
- 41
- OpenAlex
- https://openalex.org/W2001025076
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15657397
Keywords
Methadone, Oxycodone, Medicine, Opioid, Morphine
References
- The rediscovery of methadone for cancer pain management
- The Norwegian brief pain inventory questionnaire: translation and validation in cancer pain patients.
- Equianalgesic dose ratios for opioids. a critical review and proposals for long-term dosing.
- Opioid plasma concentration during switching from morphine to methadone: preliminary data
- Exposure to oral oxycodone is increased by concomitant inhibition of CYP2D6 and 3A4 pathways, but not by inhibition of CYP2D6 alone.
- Routine drug monitoring of serum concentrations of morphine, morphine-3-glucuronide and morphine-6-glucuronide do not predict clinical observations in cancer patients
- Human UGT2B7 catalyzes morphine glucuronidation.
- Rapid switching from morphine to methadone in cancer patients with poor response to morphine.
- Switching from morphine to oral methadone in treating cancer pain: what is the equianalgesic dose ratio?
- Pharmacokinetics and Pharmacodynamics of Methadone Enantiomers in Hospice Patients With Cancer Pain
- Morphine and morphine metabolite concentrations in cerebrospinal fluid and plasma in cancer pain patients after slow‐release oral morphine administration
- Methadone Pharmacokinetics are Independent of Cytochrome P4503A (CYP3A) Activity and Gastrointestinal Drug Transport: Insights from Methadone Interactions with Ritonavir/Indinavir
- Patient-controlled dose regimen of methadone for chronic cancer pain.
- Recruiting vulnerable populations for research: revisiting the ethical issues.
- A double-blind, randomized, crossover comparison between single-dose and double-dose immediate-release oral morphine at bedtime in cancer patients.
- Analytical Methods Validation: Bioavailability, Bioequivalence and Pharmacokinetic Studies
- Cytochrome P4503A4 metabolic activity, methadone blood concentrations, and methadone doses.
- Dose ratio between morphine and methadone in patients with cancer pain
- HIGH INTERINDIVIDUAL VARIABILITY OF METHADONE ENANTIOMER BLOOD LEVELS TO DOSE RATIOS
- Respiratory depression in a patient receiving oral methadone for cancer pain.
Cited by
- Long-term low-dose morphine for patients with moderate cancer pain is predominant factor effecting clinically meaningful pain reduction
- Potential Role and Challenges of Methadone in Cancer Pain Management
- Oxycodone for cancer-related pain.
- Managing Cancer Pain at the End of Life with Multiple Strong Opioids: A Population-Based Retrospective Cohort Study in Primary Care
- Opioid switching in cancer pain: From the beginning to nowadays.
- Endogenous opiates and behavior: 2013.
- Re: Fra ketobemidon til morfin eller oksykodon.
- Switching Ratio from Parenteral to Oral Methadone 1:1.2 Is Safer Compared with Ratio 1:2 in Patients with Controlled Cancer Pain: A Multicenter Randomized-Controlled Trial (RATIOMTD-010810)
- Population Pharmacokinetics of Methadone after Oral Administration in Japanese Patients with Cancer-Related Pain
- Oxycodone for cancer-related pain.
- Methadone switching for refractory cancer pain
- Pharmacological data science perspective on fatal incidents of morphine treatment.
- Schmerztherapie bei lebensbedrohlichen und lebenslimitierenden Erkrankungen
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