Designing dendrimers for biological applications
Explore this paper's citation graph
Summary
Advances in understanding of the role of molecular weight and architecture on the in vivo behavior of dendrimers, together with recent progress in the design of biodegradable chemistries, has enabled the application of these branched polymers as anti-viral drugs, tissue repair scaffolds, targeted carriers of chemotherapeutics and optical oxygen sensors.
- Type
- review
- Published
- 2005-12-01
- Cited by
- 1,897
- References
- 99
- OpenAlex
- https://openalex.org/W2001018320
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2140256
Keywords
Dendrimer, Biocompatibility, Nanotechnology, In vivo, Polymer
References
- Water-soluble dendritic unimolecular micelles: their potential as drug delivery agents.
- Dendrimers and other dendritic polymers
- Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo.
- A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.
- Effects of filtration rate on the glomerular barrier and clearance of four differently shaped molecules.
- Multiplexed detection of pathogen DNA with DNA-based fluorescence nanobarcodes
- The influence of surface modification on the cytotoxicity of PAMAM dendrimers.
- Biological evaluation of polyester dendrimer: poly(ethylene oxide) "bow-tie" hybrids with tunable molecular weight and architecture.
- Biodendrimers: new polymeric biomaterials for tissue engineering.
- Phototriggering of liposomal drug delivery systems.
- PEG-epirubicin Conjugates with High Drug Loading
- Photolabile dendrimers using o-nitrobenzyl ether linkages
- Preliminary biological evaluation of polyamidoamine (PAMAM) Starburst dendrimers.
- Gadolinium(III) DO3A macrocycles and polyethylene glycol coupled to dendrimers : Effect of molecular weight on physical and biological properties of macromolecular magnetic resonance imaging contrast agents
- Synthesis and Enzymatic Degradation of Dendrimers from (R)‐3‐Hydroxybutanoic Acid and Trimesic Acid
- Mechanism of cell death induced by cationic dendrimers in RAW 264.7 murine macrophage‐like cells
- Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions.
- Elimination of prions by branched polyamines and implications for therapeutics.
- "Cascade"- and "Nonskid-Chain-like" Syntheses of Molecular Cavity Topologies
- Influence of molecular configuration on the passage of macromolecules across the glomerular capillary wall
Cited by
- SYNTHESIS AND CHARACTERIZATION OF DOXORUBICIN CARRYING CETUXIMAB-PAMAM DENDRIMER BIOCONJUGATES
- Nanoparticulate drug carriers based on hybrid poly(D,L-lactide-co-glycolide)-dendron structures.
- Supramolecular aggregates of dendritic multishell architectures as universal nanocarriers.
- A novel micellar PEGylated hyperbranched polyester as a prospective drug delivery system for paclitaxel.
- Effects of PEGylation and acetylation of PAMAM dendrimers on DNA binding, cytotoxicity and in vitro transfection efficiency.
- Recent advances in the field of nanometric drug carriers.
- Nanomedicine in cancer therapy: Innovative trends and prospects
- Dendrimer Nanoscaffolds for Potential Theranostics of Prostate Cancer with a Focus on Radiochemistry
- Multiple antigenic peptide (MAP): a synthetic peptide dendrimer for diagnostic, antiviral and vaccine strategies for emerging and re-emerging viral diseases
- Multimodal Nanoprobes Evaluating Physiological Pore Size of Brain Vasculatures in Ischemic Stroke Models
- Ring-Opening Polymerization of Prodrugs: A Versatile Approach to Prepare Well-Defined Drug Loaded Nanoparticles**
- Synthesis of Polyester Dendritic Scaffolds for Biomedical Applications.
- Design and Applications of Protein-Cage-Based Nanomaterials.
- Perspectives on dendritic architectures and their biological applications: From core to cell.
- Precisely Defined Polymers for Efficient Gene Delivery
- A Combined Photochemical and Multicomponent Reaction Approach to Precision Oligomers.
- Acid-triggered drug release from micelles based on amphiphilic oligo(ethylene glycol)-doxorubicin alternative copolymers.
- Glyconanoparticles polyvalent tools to study carbohydrate-based interactions.
- Nanoparticle technologies for cancer therapy.
- Prostaglandin H synthase catalyzes the oxidation of 4-chlorobiphenyl metabolites, and the in vivo effects on prostaglandin production
Related papers
- The dendritic effect illustrated with phosphorus dendrimers.
- Dendrimers in medicine and biotechnology. New molecular tools
- Force Biased Molecular Dynamics Simulation Study of Effect of Dendrimer Generation on Interaction with DNA.
- An alternative convergent synthesis of dendrimers with 2,5-diarylsilole at the core
- Molecular Batteries: Ferrocenylsilylation of Dendrons, Dendritic Cores, and Dendrimers: New Convergent and Divergent Routes to Ferrocenyl Dendrimers with Stable Redox Activity
- Hydrozirconation of first-generation allyl-functionalized dendrimers and dendrimer model compounds
- Synthesis of Novel Dendrimeric Systems Containing NLO Ligands
- Biocompatibility of low molecular weight polymers for two‐phase partitioning bioreactors