Solvophobically driven folding of nonbiological oligomers.
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Summary
An aromatic hydrocarbon backbone is described that spontaneously acquires a stable helical conformation having a large cavity and is sensitive to chain length, solvent quality, and temperature.
- Type
- article
- Published
- 1997-09-19
- Cited by
- 540
- References
- 26
- OpenAlex
- https://openalex.org/W1998179757
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21449114
Keywords
Solvophobic, Intramolecular force, Folding (DSP implementation), Chemistry, Chain (unit)
References
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- Geometrically-Controlled and Site-Specifically-Functionalized Phenylacetylene Macrocycles
- Local conformational signals and the statistical thermodynamics of collapsed helical proteins.
- Synthetic molecules that fold into a pleated secondary structure in solution
- The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin.
- Helix-stabilizing interaction between tyrosine and leucine or valine when the spacing is i, i + 4.
- Principles that govern the folding of protein chains.
- Semianalytical treatment of solvation for molecular mechanics and dynamics
- Aromatic π-Stacking in Solution as Revealed through the Aggregation of Phenylacetylene Macrocycles
- Electronic spectra of tolane in a supersonic free jet: Large-amplitude torsional motion
- Protein Design: A Hierarchic Approach
- Principles of protein folding — A perspective from simple exact models
- Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics
Cited by
- Helicogenicity of solvents in the conformational equilibrium of oligo(m-phenylene ethynylene)s: Implications for foldamer research
- Poly(thiaheterohelicene): a stiff conjugated helical polymer comprised of fused benzothiophene rings.
- Computational insights into processes underlying the amine-induced fluorescence quenching of a stimuli-responsive phenol-based hexameric foldamer host.
- Amphiphilic oligocholate macrocycles: self-assembly, transmembrane nanopore formation, and noncovalent tuning
- The Synthesis and Characterization of Water Soluble Hydroindole-Based Nanostructures of Designed Three-Dimensional Architectures
- A helically folded poly(m,p-phenylene)
- Artificial Molecular Machines
- Polymers and Gels as Molecular Recognition Agents
- Photoresponsive receptors for binding and releasing anions
- Well-defined secondary structures.
- Stability of diphenylalanine pepide [i.e. peptide] nanotube studied by molecular dynamics simulation
- Interconversion of single and double helices formed from synthetic molecular strands
- Synthesis of Monodisperse Sequence‐Defined Polymers Using Protecting‐Group‐Free Iterative Strategies
- Design and synthesis of conformationally homogeneous pseudo cyclic peptides through amino acid insertion: investigations on their self assembly
- Quinone—Bodipy H-bonding interaction over π-stacking in toluene
- Energy Aspects of Thermal Molecular Switching: Molecular Thermal Hysteresis of Helicene Oligomers.
- Optically active helical poly(α,β-unsaturated ketone) from anionic polymerization of (S)-3-acrylyl-2,2′- bis(methoxymethoxy)-1,1′-binaphthyl
- Heterogeneous Foldamers from Aliphatic–Aromatic Amino Acid Building Blocks: Current Trends and Future Prospects†
- Microwave-accelerated synthesis of lengthy and defect-free poly(m-phenyleneethynylene)s via AB' and A2 + BB' polycondensation routes.
- A free radical initiated optically active vinyl polymer with memory of chirality after removal of the inducing stereogenic center.
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