Sequential karyotypic evolutions and bone marrow aplasia preceding acute myelomonocytic transformation from myelodysplastic syndrome

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Summary

Observations support the hypothesis that leukaemic change in MDS, at least in RA, occurs by stepwise clonal evolution(s), not by progressive arrest of differentiation in original MDS clone.

Type
article
Published
1984-09-01
Cited by
27
References
16

Keywords

clone (Java method), Myelodysplastic syndromes, Somatic evolution in cancer, Bone marrow, Acute myelomonocytic leukemia

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