Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation.
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Summary
Cloned cDNA encoding Osf2/Cbfa1 is identified as an osteoblast-specific transcription factor and as a regulator of osteoblasts differentiation.
- Type
- article
- Published
- 1997-05-30
- Cited by
- 4,350
- References
- 35
- Access
- Open access
- OpenAlex
- https://openalex.org/W1994596418
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16979723
Keywords
Osteoblast, Biology, Osteocalcin, RUNX2, Cell biology
References
- The Atlas of Mouse Development
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- Adipogenesis and obesity: rounding out the big picture.
- Genetic mapping of cleidocranial dysplasia and evidence of a microdeletion in one family.
- A new transcription factor family associated with human leukemias.
- Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia.
- A transcriptional hierarchy involved in mammalian cell-type specification
- Regulation of COL1A1 expression in type I collagen producing tissues: Identification of a 49 base pair region which is required for transgene expression in bone of transgenic mice
- Upstream regulatory elements necessary for expression of the rat COL1A1 promoter in transgenic mice
- Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4.
- Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors.
- Activity of the rat osteocalcin basal promoter in osteoblastic cells is dependent upon homeodomain and CP1 binding motifs.
- Development of adynamic bone in patients with secondary hyperparathyroidism after intermittent calcitriol therapy.
- 1,25-Dihydroxyvitamin D3 Inhibits Osteocalcin Expression in Mouse through an Indirect Mechanism*
- The Runt domain identifies a new family of heteromeric transcriptional regulators.
- Bone morphogenetic proteins: multifunctional regulators of vertebrate development.
- PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene.
- Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
- Animal model: skeletal anomalies in mice with cleidocranial dysplasia.
Cited by
- The Molecular Genetics of Bone Formation
- Differentially load-regulated gene expression in mouse trabecular osteocytes
- Control of TGF-beta receptor expression in bone.
- Histochemical and molecular analyses of distraction osteogenesis in a mouse model
- THE AML1‐ETO CHIMAERIC TRANSCRIPTION FACTOR IN ACUTE MYELOID LEUKAEMIA: BIOLOGY AND CLINICAL SIGNIFICANCE
- Reversible Suppression of in Vitro Biomineralization by Activation of Protein Kinase A*
- Biology and clinical utilization of mesenchymal progenitor cells.
- Rat mandibular distraction osteogenesis: part III. Gradual distraction versus acute lengthening.
- Regulation of human cbfa1 gene transcription in osteoblasts by selective estrogen receptor modulators (SERMs).
- Bone morphogenetic protein-7 (OP1) and transforming growth factor-beta1 modulate 1,25(OH)2-vitamin D3-induced differentiation of human osteoblasts.
- Hypoxia decreases Runx2/Cbfa1 expression in human osteoblast-like cells.
- Requisite roles of Runx2 and Cbfb in skeletal development
- Molecular and cellular biology of new bone formation: insights into the ankylosis of ankylosing spondylitis
- Secondary chondrocyte-derived Ihh stimulates proliferation of periosteal cells during chick development
- Human periapical granulation tissue contains osteogenic cells
- Oncogenic potential of the RUNX gene family: ‘Overview’
- Potential of biomimetic surfaces to promote in vitro osteoblast-like cell differentiation.
- Influence of three-dimensional scaffold on the expression of osteogenic differentiation markers by human dermal fibroblasts.
- Scanning Electron Microscope and Micro-CT Evaluation of Cranial Sutures in Health and Disease
- Oxysterol‐induced osteoblastic differentiation of pluripotent mesenchymal cells is mediated through a PKC‐ and PKA‐dependent pathway
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