Chemokines, chemokine receptors and small-molecule antagonists: recent developments.

Keywords

Chemokine receptor, G protein-coupled receptor, Chemokine, Receptor, Drug discovery

References

• Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene InsertionJames T. Carlton, Gregory M. Ruiz, Harold A. Mooney — 2000
• Molecular modeling on human CCR5 receptors and complex with CD4 antigens and HIV-1 envelope glycoprotein gp120.H. J. Yang, C Q Liu — 2000
• G protein-coupled receptor drug discovery: implications from the crystal structure of rhodopsin.J. Ballesteros, K. Palczewski — 2001
• Attractin: a cub-family protease involved in T cell-monocyte/macrophage interactions.Jonathan S. Duke‐Cohan, Wen Tang, Stuart F. Schlossman — 2000
• Molecular Interactions of Cyclam and Bicyclam Non-peptide Antagonists with the CXCR4 Chemokine Receptor*Lars Ole Gerlach, Renato T. Skerlj, Gary Bridger — 2001
• Urokinase Plasminogen Activator and Plasmin Efficiently Convert Hemofiltrate CC Chemokine 1 into Its Active [9–74] Processed Variant1Jalal Vakili, Ludger Ständker, Michel Detheux — 2001
• Granulocyte-Macrophage Colony Stimulating Factor Up-Regulates CCR1 in Human Neutrophils1Sara S. Cheng, Joyce Lai, Nicholas W. Lukacs — 2001
• Molecular basis for the species selectivity of the substance P antagonist CP-96,345.Bruce S. Sachais, R. Michael Snider, John Lowe — 1993
• Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100.Sigrid Hatse, Katrien Princen, Lars‐Ole Gerlach — 2001
• Lack of chemokine receptor CCR1 enhances Th1 responses and glomerular injury during nephrotoxic nephritis.Peter Topham, Vilmos Csizmadia, Dulce Soler — 1999
• CD26, let it cut or cut it down.Ingrid De Meester, Stephan Korom, Jo Van Damme — 1999
• Extension of Recombinant Human RANTES by the Retention of the Initiating Methionine Produces a Potent Antagonist (*)Amanda E. I. Proudfoot, Christine A. Power, Arlene J. Hoogewerf — 1996
• Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5.Patricia Ogilvie, Giuseppe Bardi, Ian Clark‐Lewis — 2001
• Comodulation of CXCR4 and CD26 in Human Lymphocytes*Carolina Herrera, Chikao Morimoto, Julià Blanco — 2001
• The Ligands of CXC Chemokine Receptor 3, I-TAC, Mig, and IP10, Are Natural Antagonists for CCR3*Pius Loetscher, Antonio Pellegrino, Jiang-Hong Gong — 2001
• Novel Low Molecular Weight Spirodiketopiperazine Derivatives Potently Inhibit R5 HIV-1 Infection through Their Antagonistic Effects on CCR5*Kenji Maeda, Kazuhisa Yoshimura, Shiro Shibayama — 2001
• Chemokines in pathology and medicineMarco Baggiolini — 2001
• The role of CD26/DPP IV in chemokine processing.Jo Van Damme, Sofie Struyf, A. Wuyts — 1999
• An Anti-Inflammatory Drug, Propagermanium, May Target GPI-Anchored Proteins Associated with an MCP-1 Receptor, CCR2Shoji Yokochi, Hiroyuki Hashimoto, Yoshiro Ishiwata — 2001
• A Small Molecule Antagonist of Chemokine Receptors CCR1 and CCR3Ian Sabroe, Michael J. Peck, B. J. VAN KEULEN — 2000

Cited by

• The chemokine receptor, CCR5.Paul Sjöblom — 2004
• Differential production of inflammatory chemokines by murine dendritic cell subsets.晋爾 大森 — 2004
• Characterization of oak and birch dust-induced expression of cytokines and chemokines in mouse macrophage RAW 264.7 cells.Kun Xu — 2005
• Chemokines and inflammation in heart disease: adaptive or maladaptive?Sima T. Tarzami — 2011
• Prediction of structure, function, and spectroscopic properties of G-protein-coupled receptors : methods and applications.Rene J. Trabanino — 2004
• Etude du rôle du récepteur de chimiokine CX3CR1 dans la mobilisation monocytaire induite par chimiothérapieSébastien Jacquelin — 2013
• Chemokine structure and receptor interactions.Tracy M. Handel, Elaine K. Lau — 2004
• Rôle des progéniteurs dans l’hypertension artérielle pulmonaire humaine et expérimentaleNatalia Gambaryan — 2011
• Heterotrimeric G-protein interactions and activation in chemokine receptor 5 signallingJason S. Kerr — 2010
• FOXP3 regulates metastatic spread of breast cancer via control of expression of CXCR4 chemokine receptorDorota Overbeck‐Zubrzycka — 2010
• Creating chimeras of human G-protein coupled receptors (HGPR40/43) for diabetic drug developmentDeepak Acharya — 2009
• Orphan chemokine receptors in neuroimmunology : functional and pharmacological analysis of L-CCR and HCRMichael Zuurman — 2003
• Nuclear magnetic resonance studies of CXC chemokine receptor 4 allosteric peptide agonists in solutionOlga K. Baryshnikova, Jan K. Rainey, Brian D. Sykes — 2006
• Chemokine-receptor interactions: GPCRs, glycosaminoglycans and viral chemokine binding proteins.Elaine K. Lau, Samantha J. Allen, Andro R. Hsu — 2004
• THE EXPRESSION AND CELLULAR LOCALIZATION OF CC-CHEMOKINE RECEPTOR 5 (CCR5) AFTER TRAUMATIC BRAIN INJURYVuvi Nguyen — 2010
• Differential Expression of Chemokine MCP-1, MIP-1α, MIP-2 in Lipopolysaccharide-stimulated Neonatal and Adult Rat BrainJong-Hwan Lee — 2006
• Inhibitors of selectin functions in the treatment of inflammatory skin disordersMichael P. Schön — 2005
• Chemotactic signals released during Burkitt’s lymphoma cell deathMarta Pasikowska — 2011
• Chemokine Networks and Breast Cancer MetastasisAntoine E. Karnoub, Robert A. Weinberg — 2007
• Design and synthesis of small nonpeptidergic ligands for the human cytomegalovirus-encoded receptor US28Janneke W. Hulshof — 2007

Related papers

• The chemokine family. Potential therapeutic targets from allergy to HIV infection.Amanda E. I. Proudfoot — 1998
• Heterophilic chemokine receptor interactions in chemokine signaling and biology.Birgit K. Kramp, Alisina Sarabi, Rory R. Koenen — 2011
• Slamming the DOR on chemokine receptor signaling: Heterodimerization silences ligand‐occupied CXCR4 and δ‐opioid receptorsDale Hereld, Tian Jin — 2008
• Precision-engineered Peptide and Protein Analogs: Establishing a New Discovery Platform for Potent GPCR Modulators.Kalyana Bharati Akondi, Marianne Paolini‐Bertrand, Oliver Hartley — 2021
• Dimerization of chemokine receptors in living cells: key to receptor function and novel targets for therapy.Jinhai Wang, Michael A. Norcross — 2008
• Chemokine decoy receptors: structure-function and biological properties.Raffaella Bonecchi, Benedetta Savino, Elena Monica Borroni — 2010