Randomised phase II trial of carboplatin and iproplatin in advanced urothelial cancer.
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Summary
It is concluded that the bone marrow toxicity and the chance of hypersensitivity render iproplatin an unattractive alternative to cisplatin.
- Type
- article
- Published
- 1991-11-01
- Cited by
- 14
- References
- 16
- OpenAlex
- https://openalex.org/W1993846248
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:264754244
Keywords
Carboplatin, Medicine, Toxicity, Chemotherapy, Cisplatin
References
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- Nephrotoxicity of cis‐platinum (II) dichlorodiammine
- A prospective randomized trial comparing MVAC and CISCA chemotherapy for patients with metastatic urothelial tumors.
- Iproplatin and carboplatin induced toxicities: overview of phase II clinical trial conducted by the EORTC Early Clinical Trials Cooperative Group (ECTG).
- The determinatio of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent.
- Phase II study of carboplatin in locally advanced and metastatic transitional cell carcinoma of the urinary bladder.
- Methotrexate, cisplatin and carboplatin as single agents and in combination for metastatic bladder cancer.
- Carboplatin for advanced bladder cancer.
- A randomized trial of cisplatin versus cisplatin plus methotrexate in advanced cancer of the urothelial tract.
- Comparative activity and toxicity of cis-diamminedichloroplatinum (DDP) and a combination of doxorubicin, cyclophosphamide, and DDP in disseminated transitional cell carcinomas of the urinary tract.
- Phase III comparison of cisplatin alone versus cisplatin, doxorubicin and cyclophosphamide in the treatment of bladder (urothelial) cancer: a Southeastern Cancer Study Group trial.
- The role of cisplatin-based chemotherapy in advanced urothelial tract cancer.
- Phase I clinical trial of cis-dichloro-trans-dihydroxy-bis-isopropylamine platinum(IV) (CHIP).
- Hypersensitivity reactions to CHIP.
- Combination chemotherapy with cisplatin and methotrexate in advanced transitional cell cancer of the bladder.
- A phase II study of carboplatin in metastatic transitional cell carcinoma of the bladder
Cited by
- Use of calcium channel blockers and breast carcinoma risk in postmenopausal women
- Emerging Drug Treatments for Solid Tumours
- A feasibility study of carboplatin with fixed dose of gemcitabine in "unfit" patients with advanced bladder cancer.
- The status of platinum anticancer drugs in the clinic and in clinical trials.
- A systematic overview of chemotherapy effects in urothelial bladder cancer.
- Randomized phase II/III trial assessing gemcitabine/ carboplatin and methotrexate/carboplatin/vinblastine in patients with advanced urothelial cancer "unfit" for cisplatin-based chemotherapy: phase II--results of EORTC study 30986.
- Randomized phase II/III trial assessing gemcitabine/carboplatin and methotrexate/carboplatin/vinblastine in patients with advanced urothelial cancer who are unfit for cisplatin-based chemotherapy: EORTC study 30986.
- The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
- Hypersensitivity reactions to cisplatin and carboplatin--a report on six cases.
- Hypoxia-targeted drug delivery
- Clinical evidence for the first-line treatment of advanced urothelial carcinoma: Current paradigms and emerging treatment options.
- Metallo-Drugs in Cancer Therapy: Past, Present and Future
- Nanostructured mesoporous silica carriers for platinum-based conjugates with anti-inflammatory agents.
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