Bone Marrow Stromal Stem Cells: Nature, Biology, and Potential Applications
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Summary
Bone marrow stromal cells are progenitors of skeletal tissue components such as bone, cartilage, the hematopoiesis‐supporting stroma, and adipocytes and represent an important paradigm of post‐natal nonhematopoietic stem cells, and an easy source for potential therapeutic use.
- Type
- review
- Published
- 2001-05-01
- Cited by
- 2,019
- References
- 110
- Access
- Open access
- OpenAlex
- https://openalex.org/W1993640536
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12197415
Keywords
Biology, Stromal cell, Stem cell, Bone marrow, Haematopoiesis
References
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- Death by numbers
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- Haemopoiesis in mammalian bone marrow.
- Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta
- Purified hematopoietic stem cells can differentiate into hepatocytes in vivo
- Cutting Edge Communication: Transplantation of Gene-Modified Human Bone Marrow Stromal Cells into Mouse-Human Bone Chimeras
- In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells.
- Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1.
- Precursors for fibroblasts in different populations of hematopoietic cells as detected by the in vitro colony assay method.
- The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors.
- VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
- The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro.
- Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow.
- Adipocytic cells cultured from marrow have osteogenic potential.
Cited by
- Cellular Therapy for Cardiovascular Disease Part 1 - Preclinical Insights
- Differentially load-regulated gene expression in mouse trabecular osteocytes
- Mechanisms of Tumor Metastasis to the Bone: Challenges and Opportunities
- A Serrate-expressing signaling center controls Drosophila hematopoiesis.
- Ex vivo enrichment of mesenchymal cell progenitors by fibroblast growth factor 2.
- Stem Cell Plasticity in the Hematopoietic System
- Comparison of bioengineered human bone construct from four sources of osteogenic cells
- Role of Bovine Bone Morphogenetic Proteins in Bone Matrix Protein and Osteoblast-Related Gene Expression During Rat Bone Marrow Stromal Cell Differentiation
- Bone marrow stromal stem cells for tissue engineering.
- Cells from bone marrow that evolve into oral tissues and their clinical applications.
- A method to isolate and culture expand human dental pulp stem cells.
- Bone marrow stromal cell assays – in vitro and in vivo
- MSC Frequency Correlates with Blood Vessel Density in Equine Adipose Tissue
- Altered migration and adhesion potential of pro-neurally converted human bone marrow stromal cells.
- Galanin is highly expressed in bone marrow mesenchymal stem cells and facilitates migration of cells both in vitro and in vivo.
- Disparate Companions: Tissue Engineering Meets Cancer Research
- Construction of tissue engineered nerve grafts and their application in peripheral nerve regeneration.
- Regenerative medicine and tissue engineering in orthopaedic surgery.
- Aging alters bone-fat reciprocity by shifting in vivo mesenchymal precursor cell fate towards an adipogenic lineage
- Methodology, biology and clinical applications of mesenchymal stem cells.
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