Tolerance to anticholinesterase compounds in mammals.
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Summary
Administration of multiple, sublethal doses of organophosphorus insecticides induces the development of tolerance to their toxicity, with a downregulation of the muscarinic cholinergic receptors.
- Type
- review
- Published
- 1982-01-01
- Cited by
- 144
- References
- 88
- OpenAlex
- https://openalex.org/W1991913012
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:608045
Keywords
Muscarinic acetylcholine receptor, Cholinergic, Acetylcholinesterase, Organophosphate, Pharmacology
References
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- Response of the rat ileum, uterus and vas deferens to carbachol and acetylcholine following repeated daily administration of a cholinesterase inhibitor
- Involvement of muscarinic and nicotinic receptors in behavioral tolerance to DFP.
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- Acute and subacute parathion treatment: effects on cholinesterase activities and learning in mice.
- EFFECTS OF DI‐ISOPROPYLFLUOROPHOSPHATE ON THE METABOLISM OF CHOLINE AND PHOSPHATIDYLCHOLINE IN RAT BRAIN
- Tolerance to neostigmine in rodents and its prevention by cycloheximide treatment
- Adaptation of presynaptic acetylcholine autoreceptors following long-term drug treatment.
- A permeability change in CNS tissue in chronic poisoning with disulfoton.
Cited by
- Cholinergic drug interactions and heat tolerance.
- Ameliorating Effect of Moringa ol eifera Leaf Extract on Chlorpyrifos-Induced Toxicity in the Brain of Wistar Rats
- Age-related differences in the recovery rate of brain cholinesterases, choline acetyltransferase and muscarinic acetylcholine receptor sites after a subacute intoxication of rats with the anticholinesterase agent, isofluorophate.
- Sub‐chronic exposure to paraoxon neither induces nor exacerbates diabetes mellitus in Wistar rat
- Effects of acute chlorpyrifos exposure on in vivo acetylcholine accumulation in rat striatum.
- Impaired recovery of brain muscarinic receptor sites following an adaptive down-regulation induced by repeated administration of diisopropyl fluorophosphate in aged rats.
- Cholinesterase and monoamine oxidase activity in relation to mercury levels in the cerebral cortex of wild river otters
- Dietary exposure to chlorpyrifos alters core temperature in the rat.
- Mechanisms underlying sensitivity to organophosphorus anticholinesterase compounds.
- Effect of a single dose of an acetylcholinesterase inhibitor on oxotremorine- and nicotine-induced hypothermia in mice.
- Unidirectional cross-tolerance between the carbamate insecticide propoxur and the organophosphate disulfoton in mice.
- Effects on Cholinergic Markers in Rat Brain and Blood after Short and Prolonged Administration of Donepezil
- Studies on low dose sub-acute administration of soman, sarin and tabun in the rat.
- Chronic administration of an organophosphorus insecticide to rats alters cholinergic muscarinic receptors in the pancreas.
- Acute effects of diisopropyl fluorophosphate (DFP) on autonomic and behavioral thermoregulatory responses in the Long-Evans rat.
- Determination of diisopropylfluorophosphate in rat plasma and brain tissue by headspace solid-phase microextraction gas chromatography/mass spectrometry.
- Tolerance to behavioral effects of physostigmine under interval schedules of positive or negative reinforcement
- Muscarinic receptor plasticity in the brain of senescent rats: down-regulation after repeated administration of diisopropyl fluorophosphate.
- Chronic, low-level exposure to diisopropylfluorophosphate causes protracted impairment of spatial navigation learning
- Effects of multiple oral doses of two carbamate insecticides on esterase levels in young and adult chickens
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