Evolution of dry powder inhaler design, formulation, and performance.

Keywords

Dry-powder inhaler, Medicine, Inhaler, Consistency (knowledge bases), Drug

References

• Novel Lipid-Based Hollow-Porous Microparticles as a Platform for Immunoglobulin Delivery to the Respiratory TractAdrian Bot, Thomas E. Tarara, Daniel J. Smıth — 2000
• Turbuhaler: A New Powder Inhaler for Administration of Drugs to the AirwaysKjell Wetterlin — 1988
• Respiratory Drug DeliveryPeter R. Byron — 1989
• Aerosol Electrostatics I: Properties of Fine Powders Before and After Aerosolization by Dry Powder InhalersPeter R. Byron, Joanne Peart, John N. Staniforth — 2004
• A Method for Determination of the Absolute Pulmonary Bioavailability of Inhaled Drugs: TerbutalineLars Borgström, Marita Nilsson — 1990
• The importance of particle size in response to inhaled bronchodilators.P. J. Rees, T.J.H. Clark, Folke Morén — 1982
• The bronchodilator response from inhaled terbutaline is influenced by the mass of small particles: a study on a dry powder inhaler (Turbuhaler).G Persson, J E Wirén — 1989
• Effect of powder inhaler design on drug deposition in the respiratory tractM Vidgren, A. Kärkkäinen, Panu Karjalainen — 1988
• Inappropriate inhaler use: assessment of use and patient preference of seven inhalation devices. EDICI.J. Lenney, J. Alastair Innes, G K Crompton — 2000
• A comparison of the lung deposition of salbutamol inhaled from a new dry powder inhaler, at two inhaled flow ratesGary R. Pitcairn, G. Lunghetti, Paolo Ventura — 1994
• Large porous particles for pulmonary drug delivery.David A. Edwards, Justin Hanes, Giovanni Caponetti — 1997
• Medical Aerosol Inhalers: Past, Present, and FutureAndrew R. Clark — 1995
• Comparison of the extrapulmonary beta2-adrenoceptor responses and pharmacokinetics of salbutamol given by standard metered dose-inhaler and modified actuator device.D M Newnham, D. G. McDevitt, BJ Lipworth — 1993
• Safety and efficacy of a high cumulative dose of salbutamol inhaled via Turbuhaler or via a pressurized metered-dose inhaler in patients with asthma.Eva Bondesson, K. Friberg, Samer Soliman — 1998
• On the relationship between drug and carrier deposition from dry powder inhalers in vitroTeerapol Srichana, Gary P. Martin, C Marriott — 1998
• Deposition, retention, and clearance of inhaled particles.Morton Lippmann, Donovan B. Yeates, Roy E. Albert — 1980
• Is total particle dose more important than particle distribution?Henry Chrystyn — 1997
• Issues in the use of inhaled glucocorticoids. The Asthma Clinical Research Network.A K Kamada, Stanley J. Szefler, Richard J. Martin — 1996
• Scintigraphic Assessment of Drug Delivery from the Ultrahaler Dry Powder InhalerGary R. Pitcairn, J Lim, Ann Hollingworth — 1997
• Latest advances in the development of dry powder inhalers.Ian Ashurst, Ann Malton, David Prime — 2000

Cited by

• A subcellular compartmental modeling approach to pulmonary drug developmentJingyu Yu — 2011
• A comparative study of a range of polymeric microspheres as potential carriers for the inhalation of proteins.Marisol Sánchez‐García, P. Brandon Matheny — 2008
• Functionalization of lactose as a biological carrier for bovine serum albumin by electrospraying.Ireneusz Barczak — 2011
• Influence of primary crystallisation conditions on the mechanical and interfacial properties of micronised budesonide for dry powder inhalation.Mark P. Richards, W. H. Close, T. P. Lyons — 2012
• Respirable microparticles of aminoglycoside antibiotics for pulmonary administrationChiara Parlati — 2009
• Engineering of particles for inhalationChonladda Pitchayajittipong — 2009
• The Development of A New Dry Powder InhalerXi Zhang — 2013
• Novel methodology to characterise how asthma and chronic obstructive pulmonary disease patients use their inhalers and methods to improve their inhaler technique Objective assessment of how patients use inhalersWahida Azouz — 2012
• Novolizer® multidose dry powder inhalerM Asif A Siddiqui, Greg L. Plosker — 2006
• Cationic, amphiphilic dextran nanomicellar clusters as an excipient for dry powder inhaler formulation.Mithun Varghese Vadakkan, Sujitha Saba Raj, C. Sudha Kartha — 2015
• Distribution and Cellular Uptake of PEGylated Polymeric Particles in the Lung Towards Cell-Specific Targeted DeliveryTammy W. Shen, Catherine A. Fromen, Marc P. Kai — 2015
• CFD Assessment of Respiratory Drug Delivery Efficiency in Adults and Improvements Using Controlled Condensational GrowthRoss Walenga — 2014
• Investigation and optimization of a solvent/anti-solvent crystallization process for the production of inhalation particlesSwati Agrawal — 2010
• DEM-CFD analysis of micromechanics for dry powder inhalersJiecheng Yang — 2015
• Carrier-based dry powder inhalation: Impact of carrier modification on capsule filling processability and in vitro aerodynamic performance.Eva Faulhammer, Verena Wahl, Sarah Zellnitz — 2015
• Experimental and computational study of multiphase flow in dry powder inhalersY. M. Fouda — 2014
• Use of dry powder inhalers in COPDDavid S. Wilson, M Gillion, P. J. Rees — 2007
• The micro and nano scale characterization and identification of tablet formulationsJin Zheng — 2010
• Efficient Nose-to-Lung (N2L) Aerosol Delivery with a Dry Powder InhalerP. Worth Longest, Laleh Golshahi, Srinivas Ravindra Babu Behara — 2014
• Use of inhaler devices and asthma control in severe asthma patients at a referral center in the city of Salvador, Brazil.Ana Carla Carvalho Coelho, Adelmir Souza‐Machado, Mylene dos Santos Leite — 2011

Related papers

• Improvement of drug delivery with a breath actuated pressurised aerosol for patients with poor inhaler technique.Stephen P. Newman, Alex Weisz, N Talaee — 1991
• The Genuair® inhaler: a novel, multidose dry powder inhalerHenry Chrystyn, C. Niederlaender — 2012
• Can Patients with Parkinson’s Disease Use Dry Powder Inhalers during Off Periods?Marianne Luinstra, A. W. F. Rutgers, Hilda Dijkstra — 2015
• Monitoring of Inhalation Using a Pressurized Metered-dose Inhaler (pMDI) Fitted with a Differential Pressure Sensor and Its Applications in Inhaler Technique TrainingKazuto NAKAGAWA, Fujio KOEDA, Reiko Ito — 2019
• An easy-to-use dry-powder inhalerJill P. Karpel — 2000
• COMPARISON OF SINGLE-DOSE EFFICACY OF ALBUTEROL-HYDROFLUOROALKANE BREATH-ACTUATED INHALER AND ALBUTEROL-HYDROFLUOROALKANE METERED-DOSE INHALER IN ASTHMA PATIENTS WITH POOR INHALER COORDINATING ABILITYHarold S. Nelson, Sally E. Wenzel, Lori Weisfeld — 2008
• Comparison of conventional metered dose inhaler and breath actuated inhaler in elderly patientsA. Hendry, Julie Coote, Holly Black — 1995
• Use of a new dry powder inhaler to deliver umeclidinium/vilanterol in the treatment of COPDJohn Riley, Maggie Tabberer, Natalie Richard — 2013
• Comparison of inhaled terbutaline administered by either the Turbuhaler dry powder inhaler or a metered-dose inhaler with spacer in preschool children with asthma.Sophie Laberge, Sheldon Spier, Susan Pamela Drblik — 1994