Conversion of xanthine dehydrogenase to oxidase in ischemic rat tissues.
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Summary
Polypeptide patterns for the oxidase resemble those seen following limited in vitro proteolysis of the native dehydrogenase supporting a proteolytic mechanism for the conversion of xanthine dehydrogen enzyme to oxidase in ischemic rat liver.
- Type
- article
- Published
- 1987-06-01
- Cited by
- 341
- References
- 16
- Access
- Open access
- OpenAlex
- https://openalex.org/W1990437328
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11291086
Keywords
Xanthine dehydrogenase, Xanthine oxidase, Biochemistry, Dehydrogenase, Enzyme
References
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.
- Ischemic injury in the cat small intestine: role of superoxide radicals.
- Xanthine oxidase: a critical mediator of myocardial injury during ischemia and reperfusion?
- The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (type D) into oxidase (type O) and purification of the enzyme.
- A comparison of the distribution and electron acceptor specificities of xanthine oxidase and aldehyde oxidase.
- Calcium-dependent proteolytic activity in rat liver: identification of two proteases with different calcium requirements.
- The role of oxygen free radicals in mediating the reperfusion injury of cold-preserved ischemic kidneys.
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
- Effects of free radical scavengers on renal circulation after ischaemia in the rabbit.
- Effect of allopurinol on hemorrhagic shock.
- Ischemia-induced vascular changes: role of xanthine oxidase and hydroxyl radicals.
- Super oxide and ischemia : Conversion of xanthine dehydrogenase to xanthine oxidase
Cited by
- Sources of Free Radicals
- Xanthine Oxidase Does Not Contribute to Apoptosis after Brain Hypoxia-Ischemia in Immature Rabbits
- Activated neutrophils injure the isolated, perfused rat liver by an oxygen radical-dependent mechanism.
- Molecular cloning of a cDNA coding for mouse liver xanthine dehydrogenase. Regulation of its transcript by interferons in vivo.
- Renal purine efflux and xanthine oxidase activity during experimental nephrosis in rats: difference between puromycin aminonucleoside and adriamycin nephrosis.
- Oxidative Stress, Unfolded Protein Response, and Apoptosis in Developmental Toxicity
- The importance of redox state in liver damage.
- Role of xanthine oxidase in ethanol-induced lipid peroxidation in rats.
- Superoxide dismutase: pharmacological developments and applications.
- Methods to Reduce Liver Ischemia/Reperfusion Injury
- Liver Pathology and Alcohol
- Organ Allocation
- Repopulation genetisch veränderter Kupffer-Zellen und Evaluation deren Effekte in einem akuten hepatischen Schädigungsmodell
- Nitric Oxide and Inflammation
- The Splanchnic Circulation
- The effect of ischaemia on xanthine oxidase activity in rat intestine and liver.
- Measurement of xanthine oxidase in biological tissues.
- Antiproteases modulate bronchial epithelial cell responses to endotoxin.
- Free Radicals as Mediators of Neuronal Injury
- Liver-lung interactions in critical illness.
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