BRCA1 supports XIST RNA concentration on the inactive X chromosome.
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Summary
Observations suggest that loss of BRCA1 in female cells may lead to Xi perturbation and destabilization of its silenced state.
- Type
- article
- Published
- 2002-11-01
- Cited by
- 330
- References
- 66
- Access
- Open access
- OpenAlex
- https://openalex.org/W1989841784
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:372211
Keywords
XIST, Biology, X-inactivation, Chromatin, RNA
References
- In search of the tumour-suppressor functions of BRCA1 and BRCA2
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- BRCA1-associated tumorigenesis: what have we learned from knockout mice?
- Brca1 and Brca2 expression patterns in mitotic and meiotic cells of mice
- Roles of BRCA1 and its interacting proteins
- Clinical‐cytological correlations of mammary carcinoma based upon sex‐chromatin counts A Preliminary Study
- Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.
- Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice
- Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation.
- Histone macroH2A1.2 is concentrated in the XY compartment of mammalian male meiotic nuclei
- BRCA1 required for transcription-coupled repair of oxidative DNA damage.
- The many faces of histone lysine methylation.
- Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers.
- Synergism of Xist Rna, DNA Methylation, and Histone Hypoacetylation in Maintaining X Chromosome Inactivation
Cited by
- The role of nuclear position and locus conformation in regulating V(D)J recombination of the Tcrb locus
- Increasing the yield of soluble recombinant protein expressed in E. coli by induction during late log phase.
- Dosage compensation: an intertwined world of RNA and chromatin remodelling.
- Regulatory RNAs in mammals.
- Analyse de l'expression de BARD1 dans le cancer du poumon et le cancer colorectal
- Molecular aspects of XY body formation
- X Chromosome Inactivation and Breast Cancer: Epigenetic Alteration in Tumor Initiation and Progression
- Tumour suppressors: Women only
- BRCA1 and Estrogen Signaling in Breast Cancer
- Long non-coding RNAs (lncRNAs) and viral infections
- Basal-like breast cancer: modeling its initiation and characterizing novel EGFR variants
- The cell biology of stem cells
- BRCA1: A Candidate Gene for Reproductive Isolation in House Mice
- Détermination de la structure secondaire d'une région de l'ARN Xist nécessaire à l'inactivation du chromosome X, la région des A-repeats, et identification de ses partenaires protéiques ayant un rôle structural ou fonctionnel dans l'inactivation
- Chromatin modifications on the inactive X chromosome.
- Protein function prediction by integrating sequence, structure and binding affinity information
- Notch Signaling Is Important in the Survival, Proliferation, and Self-Renewal of the Putative Breast Cancer Stem Cell Population
- Articles selected from Faculty of 1000 in July 2003
- Analysis of the role of the X/Y homologous gene family Xmr/Slyin murine spermiogenesis
- Skewed X chromosome inactivation and breast and ovarian cancer status: evidence for X-linked modifiers of BRCA1.
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