Injected Wnt RNA induces a complete body axis in Xenopus embryos.
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Summary
The results show that Wnt-1 and Xwnt-8 can induce a new and complete dorsal axis and can rescue the development of axis-deficient, UV-irradiated embryos.
- Type
- article
- Published
- 1991-11-15
- Cited by
- 529
- References
- 47
- OpenAlex
- https://openalex.org/W1989721036
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2336907
Keywords
Xenopus, Wnt signaling pathway, Biology, Embryo, Cell biology
References
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- int-1--a proto-oncogene involved in cell signalling.
- Cortical rotation of the Xenopus egg: consequences for the anteroposterior pattern of embryonic dorsal development.
- Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis.
- The organization of mesodermal pattern in Xenopus laevis: experiments using a Xenopus mesoderm-inducing factor.
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- Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures.
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- A new nomenclature for int-1 and related genes: the Wnt gene family.
- The development of wingless, a homeotic mutation of Drosophila.
- Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development.
- Lithium-induced respecification of pattern in Xenopus laevis embryos
- Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis.
- Spatial distribution of the capacity to initiate a secondary embryo in the 32-cell embryo of Xenopus laevis.
Cited by
- Mesoderm induction and development of the embryonic axis in amniotes.
- Specifying the dorsoanterior axis in frogs: 70 years since Spemann and Mangold.
- The homeobox gene goosecoid controls cell migration in Xenopus embryos.
- Intercellular signalling in mesoderm formation during amphibian development.
- Overexpressed Monomeric Human Acetylcholinesterase Induces Subtle Ultrastructural Modifications in Developing Neuromuscular Junctions of Xenopus laevis Embryos
- Induction of a secondary body axis in Xenopus by antibodies to beta- catenin
- Activation of Siamois by the Wnt pathway.
- Hindgut defects and transformation of the gastro‐intestinal tract in Tcf4−/−/Tcf1−/− embryos
- Phosphatidylinositol 3-Kinase Signaling Is Involved in Neurogenesis during Xenopus Embryonic Development*
- Frzb modulates Wnt-9a-mediated beta-catenin signaling during avian atrioventricular cardiac cushion development.
- Novel Mechanisms and Functions for Hedgehog Signaling in Development and Disease
- RNA from LPS-stirnulated macrophages induces the release of tumour necrosis factor-α and interleukin-1 by resident macrophages
- The role of Wnt in cell signaling and cell adhesion during early vertebrate development.
- Molecular dissection of Wnt3a-Frizzled8 interaction reveals essential and modulatory determinants of Wnt signaling activity
- Translational profiling through biotinylation of tagged ribosomes in zebrafish
- Mis-expression of grainyhead-like transcription factors in zebrafish leads to defects in enveloping layer (EVL) integrity, cellular morphogenesis and axial extension
- Non-acylated Wnts can promote signaling
- Pattern formation in zebrafish--fruitful liaisons between embryology and genetics.
- Transcriptional Integration of Wnt and Nodal Signals in the Establishment of the Spemann Organizer
- Analysis of Developmental Epistasis by Chromatin Immunoprecipitation in Xenopus laevis
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