Regional differences in patient characteristics, case management, and outcomes in traumatic brain injury: experience from the tirilazad trials.
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Summary
Despite the use of a strict study protocol, considerable differences in patient characteristics and case management exist between continents and among countries, reflecting variations in social, cultural, and organizational aspects.
- Type
- article
- Published
- 2002-09-01
- Cited by
- 120
- References
- 24
- OpenAlex
- https://openalex.org/W1989632957
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20365913
Keywords
Medicine, Randomized controlled trial, Traumatic brain injury, Population, Clinical trial
References
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- Survey of critical care management of comatose, head-injured patients in the United States.
- Risk factors predicting operable intracranial hematomas in head injury: Gutman MB, Moulton RJ, Sullivan I, et al J Neurosurg 77:9–14 Jul 1992
- Intercenter variance in clinical trials of head trauma--experience of the National Acute Brain Injury Study: Hypothermia.
- Clinical trials in acute myocardial infarction: should we adjust for baseline characteristics?
- Head injuries in four British neurosurgical centres.
Cited by
- Some prognostic models for traumatic brain injury were not valid.
- Incidence of Hospital-Treated Traumatic Brain Injury in the Oslo Population
- Sensitivity analysis - the effects of Glasgow Outcome Scale misclassification on traumatic brain injury clinical trials
- Detection of Pathologic Changes Following Traumatic Brain Injury Using Magnetic Resonance Imaging
- Recent developments in clinical trials for the treatment of traumatic brain injury.
- Inzidenz und Outcome nach relevantem Schädel-Hirn-Trauma
- Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients
- Outcome after severe brain trauma due to acute subdural hematoma.
- Prehospital management strategies and secondary risk factors in traumatic brain injury
- New approaches to increase statistical power in TBI trials: insights from the IMPACT study.
- Effects of Glasgow Outcome Scale Misclassification on Traumatic Brain Injury Clinical Trials
- Incidence and Outcome of Traumatic Brain Injury in an Urban Area in Western Europe over 10 Years
- An evaluation of a post-acute rehabilitation unit after five years of operations.
- Investigating gender differences in outcome following severe traumatic brain injury in a predominantly Asian population
- Incidence of Hospital-Admitted Severe Traumatic Brain Injury and In-Hospital Fatality in Norway: A National Cohort Study
- Head Injury Mortality in the Nordic Countries
- Neuroprotection in traumatic brain injury: a complex struggle against the biology of nature
- Therapeutic Time Window for Edaravone Treatment of Traumatic Brain Injury in Mice
- Large Between-Center Differences in Outcome After Moderate and Severe Traumatic Brain Injury in the International Mission on Prognosis and Clinical Trial Design in Traumatic Brain Injury (IMPACT) Study
- Clinical and neuroimaging features of severely brain-injured patients treated in a neurosurgical unit compared with patients treated in peripheral non-neurosurgical hospitals
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