A randomized clinical study of a calcium-entry blocker (lidoflazine) in the treatment of comatose survivors of cardiac arrest.
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Summary
The data do not support the routine use of this calcium-entry-blocking drug in comatose survivors of cardiac arrest, and the administration of lidoflazine after cardiac arrest was not found to be beneficial.
- Type
- article
- Published
- 1991-11-01
- Cited by
- 235
- References
- 31
- OpenAlex
- https://openalex.org/W1989358571
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5997266
Keywords
Medicine, Calcium, Anesthesia, Randomized controlled trial, Cardiology
References
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- Mechanisms of ischemic brain damage
- Early amelioration of neurologic deficit by lidoflazine after fifteen minutes of cardiopulmonary arrest in dogs.
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- Cerebral Blood Flow and Neurologic Outcome When Nimodipine is Given after Complete Cerebral Ischemia in the Dog
- Amelioration of brain damage by lidoflazine after prolonged ventricular fibrillation cardiac arrest in dogs
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- THE ROLE OF ORGANIZED MEDICINE IN PROVIDING EDUCATION ABOUT CARDIOPULMONARY RESUSCITATION *
- COMMUNITY‐BASED CARDIOPULMONARY RESUSCITATION: WHAT HAVE WE LEARNED? *
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Cited by
- La aplicación de hipotermia moderada tras la reanimación cardiaca iniciada en el medio extrahospitalario puede incrementar la supervivencia sin deterioro neurológico: estudio de casos y controles
- Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest.
- Is this patient dead, vegetative, or severely neurologically impaired? Assessing outcome for comatose survivors of cardiac arrest.
- Prehospital and emergency department care to preserve neurologic function during and following cardiopulmonary resuscitation.
- Major publications in the critical care pharmacotherapy literature: January–December 2016
- Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Str
- The pattern of irreversible brain changes after cardiac arrest in humans.
- L’arrêt cardiaque — Protection cérébrale post-arrêt cardiaque
- Neuroprotective strategies and neuroprognostication after cardiac arrest.
- Erweiterte Reanimationsmaßnahmen für Erwachsene („advanced life support“)
- Immediate Evaluation and Management of Sudden Death: Cardiopulmonary Resuscitation
- European Resuscitation Council and European Society of Intensive Care Medicine Guidelines for Post-resuscitation Care 2015: Section 5 of the European Resuscitation Council Guidelines for Resuscitation 2015.
- Cardiac arrest and therapeutic hypothermia.
- Use of epinephrine as vasopressor agent during cardiopulmonary resuscitation: another example of a double-edged sword.
- Temporal Relation of Calcium‐Calmodulin Binding and Neuronal Damage After Global Ischemia in Rats
- Use of unproven therapies in clinical practice and research: how can we better serve our patients and their families?
- Brain ischemia and reperfusion: molecular mechanisms of neuronal injury.
- Delayed therapy of experimental global cerebral ischemia with acetyl-L-carnitine in dogs.
- Mitochondrial mechanisms of cell death and neuroprotection in pediatric ischemic and traumatic brain injury
- Strain specific differences in a cardio-pulmonary resuscitation rat model.
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