Clinical, radiographic, molecular and MRI-based predictors of cartilage loss in knee osteoarthritis
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Summary
This exploratory study indicates that baseline molecular or MRI cartilage compositional markers may not provide better discrimination between knees with cartilage thinning and those without longitudinal change than simple radiographic measures, such as greater JSN score.
- Type
- article
- Published
- 2011-05-27
- Cited by
- 69
- References
- 75
- OpenAlex
- https://openalex.org/W1988774578
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:33994913
Keywords
Medicine, Osteoarthritis, Radiography, Cartilage, Knee cartilage
References
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- Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: from in vitro to in vivo.
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- Bone Marrow Edema and Its Relation to Progression of Knee Osteoarthritis
- Relationship of meniscal damage, meniscal extrusion, malalignment, and joint laxity to subsequent cartilage loss in osteoarthritic knees.
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- Uncoupling of type II collagen synthesis and degradation predicts progression of joint damage in patients with knee osteoarthritis.
- 407 WHICH BASELINE FACTORS PREDICT CARTILAGE THINNING AND THICKENING IN OA KNEES- RESULTS FROM THE A9001140 STUDY
- A comparative assessment of alignment angle of the knee by radiographic and physical examination methods.
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- The ratio of type II collagen breakdown to synthesis and its relationship with the progression of knee osteoarthritis.
- Trabecular Morphometry by Fractal Signal Analysis is a Novel Marker of Osteoarthritis Progression
- Femorotibial Cartilage Morphology: Reproducibility of Different Metrics and Femoral Regions, and Sensitivity to Change in Disease
- Atlas of individual radiographic features in osteoarthritis, revised.
Cited by
- Subchondral Bone Trabecular Integrity Predicts and Changes Concurrently with Radiographic and MRI Determined Knee Osteoarthritis Progression
- Analysis, Segmentation and Prediction of Knee Cartilage using Statistical Shape Models
- Analysis of MRI for knee osteoarthritis using machine learning
- Integrative studies on cartilage tissue engineering and joint homeostasis
- In vivo diagnostics of human knee cartilage lesions using delayed CBCT arthrography
- Early postoperative cartilage evaluation by magnetic resonance imaging using T2 mapping after arthroscopic partial medial meniscectomy.
- Quantitative Radiographic Features of Early Knee Osteoarthritis: Development Over 5 Years and Relationship with Symptoms in the CHECK Cohort
- Arthroscopic characteristics of meniscal injuries in osteoarthritic knees.
- Association of changes in delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) with changes in cartilage thickness in the medial tibiofemoral compartment of the knee: a 2 year follow-up study using 3.0 T MRI
- Rates and Sensitivity of Knee Cartilage Thickness Loss in Specific Central Reading Radiographic Strata from the Osteoarthritis Initiative
- Evaluation of separate quantitative radiographic features adds to the prediction of incident radiographic osteoarthritis in individuals with recent onset of knee pain: 5-year follow-up in the CHECK cohort.
- Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing – data from the Osteoarthritis Initiative
- The value of cartilage biomarkers in progressive knee osteoarthritis: cross-sectional and 6-year follow-up study in middle-aged subjects
- Predicting knee cartilage loss using adaptive partitioning of cartilage thickness maps
- Longitudinal Sensitivity to Change of MRI-based Muscle Cross-Sectional Area vs. Isometric Strength Analysis in Osteoarthritic Knees With and Without Structural Progression – Pilot Data from the Osteoarthritis Initiative
- dGEMRIC as a tool for measuring changes in cartilage quality following high tibial osteotomy: a feasibility study.
- Prognostic biomarkers in osteoarthritis
- The role of imaging in osteoarthritis.
- Use of imaging techniques to predict progression in osteoarthritis
- A synthetic cartilage extracellular matrix model: hyaluronan and collagen hydrogel relaxivity, impact of macromolecular concentration on dGEMRIC
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