Deficiency in cytosolic malic enzyme does not increase acetaminophen-induced hepato-toxicity.

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Summary

The data indicate that ME-1 deficiency does not adversely affect GSH-dependent detoxification, and that mod1(-/-) mice are not more sensitive to acetaminophen hepato-toxicity.

Type
article
Published
2008-07-01
Cited by
9
References
29
Access
Open access

Keywords

Glutathione, Malic enzyme, Detoxification (alternative medicine), Oxidative decarboxylation, Biochemistry

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