Identification of a Conserved B-Cell Epitope on Duck Hepatitis A Type 1 Virus VP1 Protein
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Summary
LPAPTS was identified as a VP1-specific linear B-cell epitope recognized by the neutralizing mAb 2D10, which has potential applications in the development of diagnostic techniques and epitope-based marker vaccines against DHAV-1.
- Type
- article
- Published
- 2015-02-23
- Cited by
- 25
- References
- 30
- Access
- Open access
- OpenAlex
- https://openalex.org/W1988043950
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1349845
Keywords
Epitope, Linear epitope, Monoclonal antibody, Epitope mapping, Biology
References
- Structure and Function Analysis of Therapeutic Monoclonal Antibodies against Dengue Virus Type 2
- Characterization of monoclonal antibodies against duck hepatitis type 1 virus VP1 protein.
- Foot-and-mouth disease virus can utilize the C-terminal extension of coxsackievirus A9 VP1 for cell infection.
- A hitherto-undescribed virus disease of ducks in North America.
- The effects of variations in the number and sequence of targeting signals on nuclear uptake
- Molecular characterization of a new serotype of duck hepatitis virus.
- Antigenic sites of coxsackievirus A9.
- Molecular analysis of duck hepatitis virus type 1 reveals a novel lineage close to the genus Parechovirus in the family Picornaviridae.
- Goose haemorrhagic hepatitis caused by a new subtype duck hepatitis type 1 virus.
- Monoclonal and Polyclonal Antibodies Specific for Foot and Mouth Disease Virus Type A and Type O VP1
- Isolation and identification of a novel human parechovirus.
- Antigenic analysis monoclonal antibodies against different epitopes of σB protein of Muscovy duck reovirus.
- Protective immune responses in ducklings induced by a suicidal DNA vaccine of the VP1 gene of duck hepatitis virus type 1.
- Structure of a human common cold virus and functional relationship to other picornaviruses
- Recent Korean isolates of duck hepatitis virus reveal the presence of a new geno- and serotype when compared to duck hepatitis virus type 1 type strains
- Development and evaluation of a VP1-ELISA for detection of antibodies to duck hepatitis type 1 virus.
- Differential diagnosis between type-specific duck hepatitis virus type 1 (DHV-1) and recent Korean DHV-1-like isolates using a multiplex polymerase chain reaction
- Novel vaccine strategies to T-independent antigens.
- Cell-surface Interactions of Echovirus 22*
- Nuclear targeting sequences--a consensus?
Cited by
- Molecular epidemiology of duck hepatitis a virus types 1 and 3 in China, 2010–2015
- Identification of a conserved neutralizing linear B-cell epitope in the VP1 proteins of duck hepatitis A virus type 1 and 3.
- Hepatitis Virus Infections in Poultry
- A Conserved Epitope Mapped with a Monoclonal Antibody against the VP3 Protein of Goose Parvovirus by Using Peptide Screening and Phage Display Approaches
- In Silico Prediction of Linear B-Cell Epitopes on Proteins
- Evidence of VP1 of duck hepatitis A type 1 virus as a target of neutralizing antibodies and involving receptor-binding activity.
- Identification of a New Broadly Cross-reactive Epitope within Domain III of the Duck Tembusu Virus E Protein
- Epitope Identification and Application for Diagnosis of Duck Tembusu Virus Infections in Ducks
- Mapping a Type-specific Epitope by Monoclonal Antibody against VP3 Protein of Duck Hepatitis A Type 1 Virus
- The generation and characterisation of neutralising antibodies against the Theiler's murine encephalomyelitis virus (TMEV) GDVII capsid reveals the potential binding site of the host cell co-receptor, heparan sulfate.
- Duck hepatitis A virus structural proteins expressed in insect cells self-assemble into virus-like particles with strong immunogenicity in ducklings.
- Identification of a novel linear B‐cell epitope as a vaccine candidate in the N2N3 subdomain of Staphylococcus aureus fibronectin‐binding protein A
- Protection against duck hepatitis a virus type 1 conferred by a recombinant avian adeno‐associated virus
- Identification and characterization of a novel nanobody against duck hepatitis A virus type 1.
- Expression of duck hepatitis A virus type 1 VP3 protein mediated by avian adeno-associated virus and its immunogenicity in ducklings.
- Improved one-tube RT-PCR method for simultaneous detection and genotyping of duck hepatitis A virus subtypes 1 and 3
- Identification and Application of Epitopes in EtMIC1 of Eimeria tenella Recognized by the Monoclonal Antibodies 1-A1 and 1-H2
- A Novel Peptide Isolated from a Phage Display Peptide Library Modeling Antigenic Epitope of DHAV-1 and DHAV-3
- Comparative Pathogenicity of Duck Hepatitis A Virus-1 Isolates in Experimentally Infected Pekin and Muscovy Ducklings
- Evidence of possible vertical transmission of duck hepatitis A virus type 1 in ducks.
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